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Biology of aging hub

A Knowledge Hub for Aging and Longevity

As part of our commitment to education our goal is to share evidence-based knowledge about aging and rejuvenation among the general public, the business sector, policymakers, and philanthropists. To achieve this goal we have created an educational hub to help our readers learn more about the biology of aging. Here you can find a range of topics covering the biology of aging and other related subjects.

If you are new to the topic, we recommend starting with the basics and reading our pages about why we age and what is life extension.

  • Yamanaka Factors and Partial Cellular Reprogramming

    Yamanaka Factors and Partial Cellular Reprogramming

    Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful technique may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one […]
  • What Are Sirtuins and What Do They Do?

    What Are Sirtuins and What Do They Do?

    Sirtuins are a family of seven SIRT enzymes found in the nucleus, cytoplasm, and mitochondria of human cells. These enzymes exist in nearly all species and perform many functions that […]
  • What Is Senescence and What Does It Mean?

    What Is Senescence and What Does It Mean?

    Biologists often talk about senescence, but what does senescence mean, and what does it mean when an organism or cell is senescent? What is senescence? Senescence (or biological aging) is defined as the gradual decline in function with […]
  • What is Inflammaging? Chronic Inflammation and Aging

    What is Inflammaging? Chronic Inflammation and Aging

    Today, we are going to take a look at inflammaging and the various known sources that promote this age-related inflammatory condition. What is inflammaging? The aging processes are accompanied by a chronic, smoldering background […]
  • The C57BL 6 (Black 6) Mouse Strain

    The C57BL 6 (Black 6) Mouse Strain

    The C57BL 6 or C57bl/6 (Black 6) mouse is commonly used in lifespan studies and has the distinction of being the second mammalian species, after humans, to have its entire DNA sequenced […]
  • What is CRISPR? A Summary of Gene Editing

    What is CRISPR? A Summary of Gene Editing

    What is CRISPR? CRISPR (otherwise known as “Clustered Regularly Interspaced Short Palindromic Repeat”) is a gene editing system, but it is not a human invention. It was originally part of the antiviral ‘immune […]

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