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Category: News

Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established approach This is far from the first attempt at treating osteoarthritis using stem cells. We have previously reported on a...
Foreground Clock
Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression This paper begins with a description of the elastic net, an artificial intelligence algorithm that powers the majority of biological clocks, including the Horvath biological...
EARD2023 Games for Good
In this talk, Lifespan.io President Keith Comito describes use cases for "Proof of Philanthropy" (PoP) dynamic NFTs - a new type of NFT that powers up based on tracked on-chain giving. These NFTs, built on the Polygon network, exhibit "Demi-Soulbound" properties - meaning that while the NFTs themselves are tradable, the upgradeable parameters of the...
Lower back pain
In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients [1]. Back pain is a widespread issue An overwhelming majority of people, a full 80%, have suffered from back pain at some point in their...
Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common in discussions about the biological effects of exercise: the inability of some older people to conduct exercise in any real capacity and therefore the need...
Trying to find a single cause of aging is like blinedfolded people trying to work out something is an elephant.
In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging. A problem of focus and funding The authors lament a lack of focus and funding in the field of gerontology, noting that a full 60%...