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Tag: iPSCs

LifeXtenShow on cellular rejuvenation
February 15, 2021
In this episode of X10, Nicola explains a way to epigenetically reset cells using the OSKM Yamanaka factors, putting them back into a pluripotent stem cell state. These factors have also been experimentally shown to restore cells to youth in other ways, and it is also possible to carefully use these factors to make cells...
Piglet
October 21, 2020
The latest research published in the Journal of Tissue Engineering and Regenerative Medicine has reprogrammed pig fibroblast cells into neural progenitor cells.
Mouse eye
April 21, 2020
A group of researchers has succeeded in directly reprogramming fibroblast cells into photoreceptors and transplanting them into mice, which resulted in partial restoration of vision [1]. This achievement can potentially lead to the development of cheap and effective treatments for retinopathies such as age-related macular degeneration (AMD), the leading cause of vision loss in older...
Retina
March 17, 2020
Researchers from Johns Hopkins Medicine have successfully used stem cells to repair diabetic damage to retinal blood vessels. The researchers believe that their findings will advance regenerative approaches that seek to reverse conditions such as diabetic retinopathy and other eye diseases that lead to blindness. Induced pluripotent stem cells (iPSCs) have been around for well...
Dividing cells
March 09, 2020
Researchers from AgeX Therapeutics and other organizations have proved the feasibility of reprogramming banked cells derived from a supercentenarian. Their discovery portends exciting new possibilities for aging research. What is cellular reprogramming? Cellular reprogramming is the process of reverting mature, specialized cells into induced pluripotent stem cells (iPSCs), which can develop into any cell type...
Interview with Hanadie Yousef
February 10, 2020
At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Hanadie Yousef, the co-founder and CEO of Juvena Therapeutics. Juvena is isolating proteins from embryonic stem cells that promote tissue regrowth. Can you describe in more detail Juvena's approach to developing protein therapeutics that promote tissue regeneration in the elderly?...