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Tag: Metformin

Metformin bottle
We take a look at this diabetic drug that some researchers think may slow down aging. What is metformin? Metformin is a prescription drug and is available as an tablet or an oral solution. It is a commonly used first-line medication for the treatment of type 2 diabetes and is also used in the treatment...
Nir Barzilai Interview about metformin and longevity.
Dr. Nir Barzilai is one of the leading experts in geroscience, with more than 25 years of longevity research under his belt. He is the director of the Institute for Aging Research at the Albert Einstein College of Medicine and the author of the book Age Later. He is also the leading researcher of TAME,...
Nanoparticles in blood
New research in the journal ACS Nano describes a method to improve the efficiency of NMN and metformin in the liver by using a novel nanoparticle delivery method. Nanotechnology in drug delivery  Nanotechnology is a broad field that utilizes the unique properties of extraordinarily small materials. In medicine, it has been applied in drug delivery...
Elderly resistance training
A new study published in Aging has shown that although taking metformin while undergoing resistance training limits muscle growth, it promotes youthful gene expression. The downside As the researchers of this study point out, previous research shows that taking metformin while undergoing physical resistance training (PRT) restricts the development of hypertrophy [1]. While hypertrophy is...
A recent study published in Cell Metabolism has shown that metformin, a drug that has been previously shown to be effective against some aspects of aging, ameliorates inflammaging by promoting autophagy, the cellular recycling of damaged components. Mitochondrial dysfunction, autophagy, and TH17 Mitochondrial dysfunction is one of the hallmarks of aging, the root causes that...
Metformin structure
A new study published in Aging shows that metformin, a drug that has been studied for its effects on longevity, restores mitochondrial function and repairs metabolic defects in cells from people with myotonic dystrophy, a condition that shares many of the same characteristics as aging. A genetic disease that causes age-related symptoms Myotonic dystrophy is...