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Tag: ABT-263

Mouse back
A new study published in Cell Reports has shown that the senolytic navitoclax (ABT-263) helps mice heal from spinal cord injuries [1]. The difference between mice and zebrafish The zebrafish is a well-known species studied for its regenerative abilities, so the researchers began their investigation by examining what happens to the spines of mice and...
Electric brain
There has been a great deal of interest in the last few years in the potential regenerative properties of blood factors. This has led to two broad schools of thought: one in which there are regenerative factors in young blood that can be isolated, and another in which aged blood contains regenerative factors that cannot...
Lab mouse
Researchers have discovered that removing senescent-like neurons alleviates peripheral neuropathy caused by cisplatin, a powerful chemotherapy drug, in mice. Cisplatin As the researchers of this study explain, cisplatin is a chemotherapy drug that works by causing platination in nuclear DNA, which leads to cellular failure, senescence, and death. While this is effective against cancer, this...
It has been quite a while since the community had fundraised for the MMTP senolytics project; unfortunately, the start of the experiment was delayed due to a number of issues encountered along the way. However, today, we are delighted to announce that the experiment has been approved and has finally launched! The COVID-19 situation To...