Tag: Stem Cells

Scientists have successfully used heart muscle cells created from induced pluripotent stem cells to counter the deleterious effects of heart attack in non-human primates. Reprogrammed cells for heart regeneration Yamanaka Factors - Opportunities for RejuvenationDrs. Takahashi and Yamanaka showed that they could use Oct4, Sox2, Klf4, and c-Myc (OSKM) to reprogram cells back to pluripotent, embryonic...

A placebo-controlled Phase 1/2 trial conducted in East Shanghai has found that administering umbilical cord-derived mesenchymal stem cells reduces frailty in older people. Stem cells against frailty These researchers begin by defining frailty as "a state of heightened vulnerability to potential stressors as a consequence of reduction in physiological reserves across multiple systems" [1]. This...

In Cell Stem Cell, researchers have published the results of a Phase 1 clinical trial of a treatment that uses neural stem cells (NSCs) to treat multiple sclerosis. Looking for better therapies Multiple sclerosis (MS) is a progressive disease that afflicts approximately two million people worldwide [1]. This is an autoimmune disease that causes bursts...

A new study has identified a molecule found in Saposhnikovia root as a potent mediator of tendon regeneration in rats. The results were also replicated in human cells [1]. Aging does not spare tendons Like with many tissues, the health of tendons, which are central to mobility and agility, hinges on the function of local...

Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, potentially paving the way to a new system of therapies. When signaling is critical Many of the effects of stem cells can be traced back to the EVs,...

"Stem Cell Therapy: A Rising Tide" by Neil Riordan is a comprehensive exploration of stem cell therapy along with its potential benefits, limitations, and prospects. The father of mesenchymal stem cell research, Arnold Caplan, dubbed Riordan as a pioneering figure in stem cell research and application. Therefore, it is no surprise that Riordan brings an...