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Tag: Parkinson's

Common Aggregate
Research funded by the National Institutes of Health and published in Cell has thoroughly described a little-known amyloid aggregate that accumulates in the brains of people suffering from multiple proteostasis-related neurological disorders. Three classes of pathology, one protein fragment The authors of this study list three different classes of neurodegenerative protein disorders: TDP-43 proteinopathies, such...
Parkinson's
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson's disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson's disease, which causes damage to the portion of the brain responsible for movement, is widely known to be caused by the aggregation of α-synuclein. This...
Neuron Connections
Researchers have identified an important mechanism of neurodegeneration that may be useful in treating age-related diseases such as Alzheimer’s and dementia [1]. These neurons must die Age-related neurodegenerative diseases, including Parkinson’s and Alzheimer’s, have become more prevalent mostly because of the successes of modern medicine. Today, more people become old enough to fall prey to...
Foods rich in niacin
A clinical trial on the effectiveness of niacin supplementation in Parkinson's disease patients has recently been published in Frontiers in Aging Neuroscience. The link between niacin and Parkinson’s disease Niacin is a form of vitamin B3 that is commonly manufactured as a dietary supplement. Patients with Parkinson’s have considerably lower levels of vitamin B3 compared...
RNA
A massive RNA sequencing effort has identified changes in microRNA associated with Parkinson's. Some of the changes correlated with disease progression, holding out hope that they could be useful as prognostic or diagnostic biomarkers to help guide research and evaluate potential therapies. Pinning down Parkinson's Although Parkinson's disease is the second most common neurodegenerative disease...
cute white rat
In a new study, a group of researchers report on their success in priming stem cells to differentiate into dopaminergic neurons in rat brains. Loss of these neurons is a major cause of Parkinson’s disease [1]. Less neurons, more Parkinson's Neuronal degeneration is the culprit behind several age-related disorders, including Parkinson's disease (PD), which affects...