Help us: Donate
Follow us on:
×

Menu

Back

Tag: Fibrosis

Fibrotic liver
A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts, cells that are a part of organ fibrosis. It also documents the link between telomere attrition and cellular senescence, two of the hallmarks of aging....
Lung branches
A new review published in the American Journal of Respiratory Cell and Molecular Biology discusses the causes of, and potential treatments for, idiopathic pulmonary fibrosis (IPF). Fibrosis, but not focused on fibroblasts In the lungs, the trachea (airway) breaks out into a tree-like system of nodes. Each branch ends in alveoli, which are responsible for...
Scarring
Researchers have been trying to find out how to stop the formation of scars for decades, and now, thanks to a new mouse study, they are one step closer. Scars are a fast but poor repair Many of us have scars of one kind or another from accidents or surgery. As unpleasant as they are,...
CGI of kidneys
A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The new study not only clearly demonstrates this link but also provides mouse models which can be used to study – and perhaps eventually address –...
The Journal Club returns live on our Facebook page on Wednesday, March 31, at noon Eastern time. This month, we will be taking a look at a new paper from Dr. Maria Blasco and her team that discusses how short and dysfunctional telomeres sensitize the kidneys to develop fibrosis [1]. Accumulation of short telomeres is...
Lungs in orange
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex predator of humanity. According to one study, fibrotic diseases that cause organ failure are responsible for around 45% of all deaths in the United States...