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Tag: Fibrosis

CGI of kidneys
March 25, 2021
A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The new study not only clearly demonstrates this link but also provides mouse models which can be used to study – and perhaps eventually address –...
March 23, 2021
The Journal Club returns live on our Facebook page on Wednesday, March 31, at noon Eastern time. This month, we will be taking a look at a new paper from Dr. Maria Blasco and her team that discusses how short and dysfunctional telomeres sensitize the kidneys to develop fibrosis [1]. Accumulation of short telomeres is...
Lungs in orange
February 23, 2021
Scientists have successfully reversed persistent lung fibrosis in mice by overexpressing the SIRT3 protein in lung macrophages [1]. Fibrosis: not knowing when to stop Fibrosis may be the true apex predator of humanity. According to one study, fibrotic diseases that cause organ failure are responsible for around 45% of all deaths in the United States...
Health shield
November 25, 2020
Recent research published in Nature Biomedical Engineering has shown a way to dramatically improve the feasibility of transplanting therapeutic cells, particularly pancreatic islet cells, while protecting them from the recipient’s immune response. PancreasThe pancreas primarily functions as an exocrine and endocrine gland. It supports digestion by excreting digestive enzymes into the small intestines to break...
August 18, 2020
The Journal Club returns August 25th at 13:00 EDT live on our Facebook page where Dr. Oliver Medvedik will be taking a look at the new study by Dr. Maria Blasco from the CNIO, which shows that telomerase therapy can address fibrosis in normally aged mice and not just mouse models of the disease. Short/dysfunctional...
March 02, 2018
In the February edition of Journal Club, we talked about the new publication by Dr. Maria Blasco which demonstrates the reversal of pulmonary fibrosis in a new mouse model. This is an important step forward for the potential treatment of fibrosis as currently there are no effective cures for this disease. We also wrote an...