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Tag: Dementia

Synaptic Transmission
Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer's disease, still defy current treatment options, impeding attempts to increase human lifespan. According to the theory of competing risks, we cannot hope to meaningfully increase lifespan until all...
Blood cells in an artery
A mouse study published in Aging Cell has outlined the similarities between artificially restricted cerebral blood flow and the reduced blood flow associated with aging. Aiming to understand vascular dementia Prior research has shown that reduced cerebral blood flow, known as hypoperfusion, results in vascular dementia and brain atrophy through multiple mechanisms, including neuroinflammation and...
Elderly woman sleeping
Quality sleep is one of the foundations of health, and a new study suggests that poor sleep quality is a major risk factor for developing Alzheimer’s disease and other dementias. Dementia is a rising global problem Worldwide, close to fifty million people currently live with Alzheimer's disease or other forms of dementia. According to the...
For the first time in an animal model, researchers at the Lewis Katz School of Medicine at Temple University showed that the tau pathology that accompanies Alzheimer’s disease can be reversed using the asthma drug zileuton [1]. Abstract Previous studies showed that the leukotrienes pathway is increased in human tauopathy and that its manipulation may...
Researcher Dr. Dena Dubal, from the University of California San Francisco, is considering a new approach to combat neurodegenerative diseases, such as Alzheimer’s disease and dementia, using a protein known as klotho. Aging is the foundation of age-related diseases Instead of trying to understand each of these diseases and the complex mechanisms unique to both,...