Γ—

Get Up to $500,000 for Aging Research with Impetus

Impetus Grants Round 3: Apply for a research grant by September 15th

Share







Impetus grants are designed to be easy and fast to apply for.Impetus grants are designed to be easy and fast to apply for.

Earlier this month, Impetus Grants announced its third round of funding, with 10 million from the Rosenkranz and Hevolution foundations.

Previously, the program conducted two grant rounds, bringing 114 new projects and 50 new labs into the space, giving away more than 24 million dollars for a β€œnew kind of science”. Now, some of these projects are starting to bear fruit. Several have been published in big-name journals like Nature, despite first being labeled as β€œlow probability of success”, including extending lifespan in worms powered by light, clinical trials on aging ovaries, programmable RNA sensors as a therapeutic intervention, and three new rapamycin clinical trials in humans.

From double-blinded reviews to the publication of negative results to a focus on β€˜upside risk’, many of the program’s features have long been advocated for in traditional grant-making processes. Anyone, of any academic or scientific background, can write an application over the weekend and get up to $500,000 for a moonshot idea in aging. The program aims to attract as many new scientists as possible to the mission of tackling aging.

The grant focuses on aging research, with the following four areas being of particular interest:

1. Proposals that stress-test popular theories of aging

ADVERTISEMENT

Recently, yet another study has been published showing that eliminating senescent cells is detrimental for the organism, this time in the lungs of mice. Currently, researchers are raising questions about therapies aimed at controlling cellular senescence. Impetus would like to fund more proposals investigating this question, as the organization does not expect this direction to be supported by traditional funding.

2. Proposals that stress-test popular protocols for extending lifespan

In the last two years, partial cellular reprogramming has become the central topic of many companies and research groups. However, it hasn’t been rigorously investigated or reported as to what extent rejuvenating effects of partial reprogramming happen due to the depletion (death) of aged cells in the reprogramming pool. Given the susceptibility of aged cells to undergo apoptosis in reprogramming, Impetus believes that investigating this question further would be critical for improving current anti-aging reprogramming protocols.

3. Category-openers or proposals that test novel mechanisms and approaches to reversing aging

In the previous round, Impetus funded a project that was deemed to be very risky by reviewers, as it didn’t have any research precedents. That work, “Extending lifespan in C. elegans by controlling mitochondrial membrane potential with light”, has now been published in Nature Aging. With this proposal, the group pioneered a concept of external energy replacement for treating aging, creating a novel branch of aging research. Impetus is looking forward to funding more proposals that develop absolutely new paradigms and ways of thinking about geroscience, even if it comes with risks, such as in this case.

4. Translation of preclinical findings

Impetus will continue looking into creating greater worldwide access to improved model organisms in order to make early large-animal studies less prohibitively expensive. The organization will also continue supporting a great number of proposals that test the context-dependence of known aging modulators. According to program co-founder and director Lada Nuzhna,

β€œThe premise of Impetus is not only to bring more money into geroscience but rather to bring it to an overlooked kind of science. Overlooked can mean any idea that did not or would not receive traditional funding for reasons unrelated to the quality of the work itself.”

Applications are open until September 15th, 2023, so if you have a research proposal, apply for a grant today! If you need help with how to apply, check out the grant application guide.

ADVERTISEMENT

An advertisement banner for PartiQular supplements.

To do this, we need your support. Your charitable contribution tranforms into rejuvenation research, news, shows, and more. Will you help?
CategoryNews

Related Organizations

About the author

Steve Hill

Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 600 articles on the topic, interviewed over 100 of the leading researchers in the field, hosted livestream events focused on aging, as well as attending various medical industry conferences. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Swiss Monthly, Keep me Prime, and New Economy Magazine. Steve is one of three recipients of the 2020 H+ Innovator Award and shares this honour with Mirko Ranieri – Google AR and Dinorah Delfin – Immortalists Magazine. The H+ Innovator Award looks into our community and acknowledges ideas and projects that encourage social change, achieve scientific accomplishments, technological advances, philosophical and intellectual visions, author unique narratives, build fascinating artistic ventures, and develop products that bridge gaps and help us to achieve transhumanist goals. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project.
No Comments
Write a comment:

*

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.