Month: April 2024

Scientists have identified the proteins FOXF1 and its downstream target FZD4 as potential targets for treating lung cancer. Upregulating them helps to normalize vasculature in the tumor area and suppresses this lethal type of cancer [1]. Lung cancer and vasculature Lung cancer remains one of the deadliest diseases in the world, accounting for 22% of...

In Aging Cell, researchers have published evidence that downregulating a key aspect of lipid metabolism harms mitochondrial function, but only in cells taken from younger people. Fat regulation at the cellular level Perilipins (PLINs) are proteins that regulate the use of fats (lipids) within cells. This paper focuses on PLIN2, which has previously been investigated...

Berlin's event landscape is growing: Longevity Week will take place in the German capital for the first time from May 6-12, 2024. The opening event will take place on May 6th at the Langenbeck-Virchow-Haus in Berlin Mitte near the Charité hospital. A total of 15 events will be organised throughout the city. Speakers include, among...

Scientists have discovered that frequently interrupting prolonged sitting with physical activity, such as short walks or squats, can help control glucose levels in overweight and obese males [1]. Don’t just sit there! Prolonged sitting is the curse of modern times. It has been associated with various health problems, such as diabetes, poor heart health, weight...

Researchers have published the results of a study in Aging Cell, finding some evidence that type 2 diabetes causes accelerated aging. Later-generation clocks only Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many...

The authors of a recent paper published in GeroScience used an alternative statistical test to reanalyze data from the Interventions Testing Program and identified additional life‑extending compounds [1]. The crucial step of data analysis A typical biological experiment can be divided into three stages: planning, executing, and results analysis. The last part can be done...