Month: November 2018

A couple of days ago, news about the first designer babies has shaken the world. A Chinese researcher, Jiankui He, and his team at the Southern University of Science and Technology of China have been recruiting couples in order to create the world’s first babies with artificially increased resilience to HIV. The embryos were modified...

Today, we want to discuss a review published in the journal Science, as it provides a whistle-stop tour of caloric restriction, intermittent fasting, and time-restricted feeding [1]. There is a considerable amount of data supporting the effects of caloric restriction and similar dietary approaches on both health and lifespan in multiple species. In general, the...

A new study takes a look at the relationship between metabolism, aging, and type 2 diabetes and in particular the mTORC1 protein complex, part of the mTOR pathway. The mTOR pathway The mechanistic target of rapamycin (mTOR) pathway is a major part of metabolism and is one of four major pathways that control it; collectively,...

Many people are concerned that vastly extended healthy lifespan might lead us to catastrophic overpopulation, and the best way to mitigate this fear is probably to talk to an experienced demographer. To learn more about this and other interesting questions related to life extension, we spoke to Drs. Leonid Gavrilov and Natalia Gavrilova, respectively Principal...

Today, we want to highlight a recent, small-scale study looking at NAD+ and how it declines with age in the plasma. The researchers looked at various NAD+ metabolites across age groups and found that the amounts of some of them, particularly NAD+ itself, are significantly smaller in older people than younger ones [1]. This is...

A new palm-sized testing system has been developed to measure the levels of aging biomarkers circulating in the body. The new biomarker system, called Click-A+Chip, was developed by Sarah Balderston and Mandeep Sandhu, who are part of the Keck Graduate Institute team led by Assistant Professor of Medical Diagnostics and Therapeutics Kiana Aran. This miniature...