November 29, 2018
A couple of days ago, news about the first designer babies has shaken the world. A Chinese researcher, Jiankui He, and his team at the Southern University of Science and Technology of China have been recruiting couples in order to create the world’s first babies with artificially increased resilience to HIV. The embryos were modified...
November 28, 2018
Today, we want to discuss a review published in the journal Science, as it provides a whistle-stop tour of caloric restriction, intermittent fasting, and time-restricted feeding [1]. There is a considerable amount of data supporting the effects of caloric restriction and similar dietary approaches on both health and lifespan in multiple species. In general, the...
November 26, 2018
Since 2007, the Project for Awesome, simply known as P4A, has been helping to make the world a better place. It is an initiative of the Foundation to Decrease World Suck, a Montana-based charitable organization run by Hank and John Green, and their plan is simple: to make the world suck less. So, how is...
November 15, 2018
A new study takes a look at the relationship between metabolism, aging, and type 2 diabetes and in particular the mTORC1 protein complex, part of the mTOR pathway. The mTOR pathway The mechanistic target of rapamycin (mTOR) pathway is a major part of metabolism and is one of four major pathways that control it; collectively,...
November 14, 2018
Many people are concerned that vastly extended healthy lifespan might lead us to catastrophic overpopulation, and the best way to mitigate this fear is probably to talk to an experienced demographer. To learn more about this and other interesting questions related to life extension, we spoke to Drs. Leonid Gavrilov and Natalia Gavrilova, respectively Principal...
November 09, 2018
Today, we want to highlight a recent, small-scale study looking at NAD+ and how it declines with age in the plasma. The researchers looked at various NAD+ metabolites across age groups and found that the amounts of some of them, particularly NAD+ itself, are significantly smaller in older people than younger ones [1]. This is...