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A recent study from Penn State University may shed more light on the link between telomeres, aging, and why caloric restriction appears to influence them. Telomeres are linked to aging Telomeres are small protective caps on the ends of our chromosomes that guard our DNA. Telomere attrition, in which these caps slowly erode, is a...

LongX, an initiative dedicated to providing early-career avenues into longevity, announced a call for applications for its 2024 Xplore Program. The program lasts from June 2024 until September 2024 and features a one-month longevity primer course followed by the opportunity to gain educational experience with a company operating in the longevity biotechnology sector. The program...

Researchers have found a new protein target for senescence-related kidney diseases and published their findings in Aging Cell. Kidney disease and fatty acid use Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they emit...

A recent study saw researchers associated with Cellvie demonstrate significant improvements to mitochondria and muscle function in aged mice by injecting additional mitochondria [1]. Mitochondrial dysfunction is a reason we age Why We Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species...

A placebo-controlled Phase 1/2 trial conducted in East Shanghai has found that administering umbilical cord-derived mesenchymal stem cells reduces frailty in older people. Stem cells against frailty These researchers begin by defining frailty as "a state of heightened vulnerability to potential stressors as a consequence of reduction in physiological reserves across multiple systems" [1]. This...

A study published in Human Nutrition & Metabolism found that prolonged intermittent fasting causes the expression of genes involved in autophagy, the inflammasome, and senescence to change [1]. Fasting your way to better health and longevity? Previous research has linked fasting to delaying the onset of age-related diseases and longevity along with positive outcomes in...