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Tag: Oxidative Stress

A long-eared, long-tailed mouse
January 14, 2021
Activation of a genetic pathway controlled by the NRF2 gene reduces age-related hearing loss, according to a new study [1]. In the long run, drugs or treatments that target this pathway could help us keep our hearing sharp as we get older. It's getting harder and harder to hear Age-related hearing loss is extremely common,...
May 09, 2019
A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells (CSCs) of the breast [1]. While antibiotics are not normally effective against cancer, and Vitamin C is more well-known for its role in supporting the...
August 29, 2018
In a new study, researchers have identified a direct link between mitophagy and inflammation. Aging is accompanied by rising levels of oxidative stress, which is primarily caused by our cellular power plants, the mitochondria. As we age, our mitochondria start to produce an increasing amount of oxidized molecules known as reactive oxygen species (ROS), which...
June 25, 2018
According to scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, or DKFZ), the enzyme TXNIP, which inhibits the enzyme TRX-1, might be a regulator of aging and might be a viable candidate for future interventions against age-related diseases [1]. Study summary The “free radical theory of aging” suggests that reactive oxygen species (ROS) are...
April 15, 2018
The mitochondria are the powerhouses of the cell, producing ATP, a kind of universal energy used in cellular functions. Mitochondrial dysfunction is an important part of the aging process. As cells age, the effectiveness of the respiratory chain diminishes, increasing electron leakage and reducing ATP generation [1]. As mitochondria become more dysfunctional with age, there...