January 16, 2023
A new paper published in Nutrients shows that the well-known NAD+ precursor NMN alleviates lung injury caused by silicate inhalation in wild-type mice. An antioxidant approach to a common problem What is Nicotinamide Mononucleotide? A Summary of NMNNicotinamide mononucleotide (NMN) is a precursor of the coenzyme NAD+, which serves critical functions in our cells. The...
December 15, 2022
Publishing in Free Radical Biology and Medicine, a team of Chinese researchers has investigated the potential role of autophagy in fighting oxidative stress and potentially staving off age-related macular degeneration (AMD). AMD, oxidative stress, and autophagy AMD comes in two major forms. In the nonexudative (dry) form, material builds up behind the retina, while in...
January 12, 2022
A recent study published in Biogerontology has discovered a potential new aging biomarker and longevity therapeutic target [1]. Isthmin 1 (Ism1) in aging fish Ism1 is not a well-known protein, but it has been shown to play a role in multiple aspects of biology. It contributes to tumor suppression [2,3], is essential during organ development...
July 06, 2021
Researchers from Hebei Medical University in China have found that testosterone supplementation ameliorates age-related brain dysfunction in male rats. A focus on mitochondria Why we Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells and cause increasing levels of...
January 14, 2021
Activation of a genetic pathway controlled by the NRF2 gene reduces age-related hearing loss, according to a new study [1]. In the long run, drugs or treatments that target this pathway could help us keep our hearing sharp as we get older. It's getting harder and harder to hear Age-related hearing loss is extremely common,...
May 09, 2019
A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells (CSCs) of the breast [1]. While antibiotics are not normally effective against cancer, and Vitamin C is more well-known for its role in supporting the...
