Tag: Osteoporosis

Researchers publishing in Aging have uncovered some of the molecular mechanisms behind why mesenchymal stem cells (MSCs) do and don't differentiate into bone-building osteoblasts, unlocking a potential new approach to osteoporosis. A matter of cellular fate MSCs are downstream of pluripotent stem cells: they can differentiate into multiple cell types, but not every somatic cell...

Studying a large British cohort, scientists have found that vegetarians have an increased risk of hip fracture compared to regular meat eaters, but pescatarians and occasional meat eaters do not [1]. Diet and brittle bones Hip fracture is one of the injuries most associated with aging. While hip fracture itself is treatable, it can easily...

Researchers publishing in Aging have investigated zoledronic acid, a drug already used to protect bones and fight osteoporosis, for its activity against cellular senescence. An approved drug with established effects Zoledronate has already been approved by the FDA for clinical use, as it has been prescribed to prevent bone fractures in vulnerable people for more...

A paper published in Experimental Gerontology has detailed how a bacterially derived compound may be useful in fighting osteoporosis. Osteoblasts and osteoclasts BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to...

Scientists have found that animal protein consumption positively correlates with bone density in older adults. Things become more complicated regarding plant protein [1].   Too little or too much? Just how much protein people should consume has been a point of contention. Decades-old research, performed mainly in underdeveloped communities, shows that protein deficiency can be...

In a new study published in Bone Research, Japanese researchers established a novel drug screening system and identified a promising compound to treat age-associated muscle and bone frailty [1]. Musculoskeletal system Muscle health and bone health are tightly interconnected. Various muscular dystrophies are a great example: disease-caused muscle wasting leads to skeletal deformities, which prompts...