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Tag: Osteoporosis

November 20, 2020
As we reported yesterday on Lifespan.io, the common supplement alpha-ketoglutarate has been shown in a rodent study to combat osteoporosis, the age-related loss of bone tissue caused by an imbalance between bone-building and bone-destroying cells. Today, we present a related video from the Sheekey Science Show, a popular science show that often discusses aging and...
November 19, 2020
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur by giving our...
September 21, 2020
Researchers from the University of Geneva have shown that a warm environment improves bone strength and highlights a related link with gut microbiome composition. These findings also pave the way for novel therapies for the treatment of osteoporosis. Turning up the heat Osteoporosis is an age-related bone disease typified by the loss of bone density,...
September 16, 2020
Because of bone's natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
June 09, 2020
A group of Japanese scientists has found that advanced glycation end products (AGEs) tend to accumulate in osteoblasts with age, inducing apoptosis via endoplasmic reticulum stress. This mechanism likely contributes to the development of osteoporosis [1]. AGEs and age Advanced glycation end-products, fittingly abbreviated as AGEs, are proteins or lipids that have had sugars attached...
May 26, 2020
Recently, a group of South Korean scientists has analyzed the blood proteome of mice to determine how it changes with age and to identify aging-related proteins that have previously eluded researchers. After identifying several such proteins, the group focused on a specific protein, cadherin-13, that seems to prevent age-related bone loss [1]. The plasma proteome...