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Tag: MSCs

Exosomes
A new study in Aging Cell has shown extracellular vesicles from stem cells to extend healthspan and reduce cellular senescence in vitro and in mice. Stem cell exhaustion is a well-studied hallmark of aging that occurs in multiple model organisms and multiple tissue types in humans. This has led to the hypothesis that bolstering these...
cute white rat
In a new study, a group of researchers report on their success in priming stem cells to differentiate into dopaminergic neurons in rat brains. Loss of these neurons is a major cause of Parkinson’s disease [1]. Less neurons, more Parkinson's Neuronal degeneration is the culprit behind several age-related disorders, including Parkinson's disease (PD), which affects...
Image of knee inflammation caused by osteoarthritis
A collective of scientists has shown that osteoarthritis can be alleviated by guiding skeletal stem cells towards differentiation into chondrocytes, which are responsible for producing healthy cartilage [1]. Osteoarthritis (OA) is a classic example of an age-related disease. While almost non-existent in younger people, it affects as much as half of the over-65 population worldwide....
The circadian clock
Researchers have found that CLOCK, a protein that regulates the circadian cycle of our cells, also fights cellular senescence by promoting chromatin stability [1]. Since its very beginning, life on Earth had to adapt to our planet's natural 24-hour rotation cycle. Rising to the challenge, nature invented biological mechanisms called circadian clocks (from the Latin...
COVID-19 Therapeutics Roadmap
The COVID-19 pandemic is dominating the news as countries around the world work hard to control the spread of the disease. Social distancing can help "flatten the curve" and prevent the overload of healthcare systems; however, there is a large percentage of people who develop serious complications after getting the virus. The global community is...
COVID-19
A study published in Aging and Disease shows the effectiveness of mesenchymal stem cell (MSC) therapy against a deadly immune reaction caused by COVID-19. While scientists all over the world are working on a vaccine that would be effective against the SARS-CoV-2 coronavirus, which is responsible for the COVID-19 pandemic, a group of researchers from...