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Tag: MSCs

April 09, 2020
The COVID-19 pandemic is dominating the news as countries around the world work hard to control the spread of the disease. Social distancing can help "flatten the curve" and prevent the overload of healthcare systems; however, there is a large percentage of people who develop serious complications after getting the virus. The global community is...
March 16, 2020
A study published in Aging and Disease shows the effectiveness of mesenchymal stem cell (MSC) therapy against a deadly immune reaction caused by COVID-19. While scientists all over the world are working on a vaccine that would be effective against the SARS-CoV-2 coronavirus, which is responsible for the COVID-19 pandemic, a group of researchers from...
April 18, 2019
The results of a clinical trial using bone marrow-derived mesenchymal stromal cells (MSCs) to treat late-stage knee osteoarthritis were published recently, and they came back positive. The trial included both phase 1 and 2 and was designed to determine the safety and efficacy of MSC stem cell therapy. A battery of tests During the trial,...
March 14, 2019
Today, we want to point out a new study suggesting that senescent cells in bone marrow cell populations contribute to the decline of the hematopoietic system, particularly the hematopoietic stem and progenitor cells (HSPCs) that live in the bone marrow and produce our blood cells [1]. The hematopoietic system and immunosenescence The hematopoietic system is...
December 07, 2018
Today, we want to highlight results from human trials in which stem cell transplants have been shown to reduce age-related frailty. Age-related frailty and stem cell transplants Currently, there are no specific approved therapies to address age-related frailty, which can cause elderly people to suffer potentially fatal falls and injuries. There has been considerable interest...
September 27, 2018
A recent open-access mouse study published by Xi'an Institute of Tissue Engineering and Regenerative Medicine scientists in the journal Bone Research describes how the ALPL gene affects bone aging and suggests that metformin might constitute a viable therapeutic option to prevent it [1]. Study abstract Mutations in the liver/bone/kidney alkaline phosphatase (Alpl) gene cause hypophosphatasia...