Help us: Donate
Follow us on:
×

Menu

Back

Tag: MSCs

Assisted living
A paper published in the journal of the Alzheimer's Association has revealed the results of a Phase 1 clinical trial of stem cells for Alzheimer's disease. Using stem cells for their signals While stem cells, including the mesenchymal stem cells (MSCs) of which Lomecel-B consists, are well-known for their ability to differentiate into other cells,...
Exosomes
A new study in Aging Cell has shown extracellular vesicles from stem cells to extend healthspan and reduce cellular senescence in vitro and in mice. Stem cell exhaustion is a well-studied hallmark of aging that occurs in multiple model organisms and multiple tissue types in humans. This has led to the hypothesis that bolstering these...
cute white rat
In a new study, a group of researchers report on their success in priming stem cells to differentiate into dopaminergic neurons in rat brains. Loss of these neurons is a major cause of Parkinson’s disease [1]. Less neurons, more Parkinson's Neuronal degeneration is the culprit behind several age-related disorders, including Parkinson's disease (PD), which affects...
Image of knee inflammation caused by osteoarthritis
A collective of scientists has shown that osteoarthritis can be alleviated by guiding skeletal stem cells towards differentiation into chondrocytes, which are responsible for producing healthy cartilage [1]. Osteoarthritis (OA) is a classic example of an age-related disease. While almost non-existent in younger people, it affects as much as half of the over-65 population worldwide....
The circadian clock
Researchers have found that CLOCK, a protein that regulates the circadian cycle of our cells, also fights cellular senescence by promoting chromatin stability [1]. Since its very beginning, life on Earth had to adapt to our planet's natural 24-hour rotation cycle. Rising to the challenge, nature invented biological mechanisms called circadian clocks (from the Latin...
The results of a clinical trial using bone marrow-derived mesenchymal stromal cells (MSCs) to treat late-stage knee osteoarthritis were published recently, and they came back positive. The trial included both phase 1 and 2 and was designed to determine the safety and efficacy of MSC stem cell therapy. A battery of tests During the trial,...