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Tag: Microglia

Amyloid beta plaques
In a study published in Cell Stem Cell, researchers have investigated a way to repopulate the brain with functional cells in order to fight back against Alzheimer's disease. A gene with a microglial function Various allelles of the apolipoprotein E (APOE) genes are well-known for their contributions to, or defenses against, Alzheimer's, as they affect...
Astrocyte
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia BrainThe brain is perhaps the most important organ in the body. While many organs are critical to our survival, the brain contains the self. It is responsible...
Severe brain disease
In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on genetics and environment One out of twenty Americans over 85 have Parkinson's disease [1], and seven out of twenty have Alzheimer's [2]. While genes are...
COVID on the brain
Researchers have shown that even mild SARS-CoV-2 infection can cause lingering neurological symptoms. These findings might shed light on the infamous "long COVID" [1]. Mild doesn't mean harmless COVID survivors sometimes experience cognitive symptoms, such as β€œbrain fog”, that can linger for months. Those symptoms can be debilitating, affecting work performance and learning, and they...
Mouse eating
Publishing in Microbiome, a team of researchers has ascertained multiple physical effects of aging gut flora in mice. Antibiotics and fecal transfers The researchers used three groups of mice: young (3 months), old (18 months), and aged (24 months). Young and old groups were divided into a control group, an antibiotics group, and three recipient...
Microglia
Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is of utmost importance for geroscientists, since the brain is the one organ that cannot be replaced, and microglia are the brain's resident immune cells. Reacting...