Tag: Inflammation

Nature Communications has recently published a paper discussing the genetic sources of C-reactive protein, a well-known biomarker of chronic inflammation. What is Inflammaging? Chronic Inflammation and AgingThe aging process is accompanied by a chronic, smouldering background of inflammation that researchers call “inflammaging”.Read More An extremely broad study with a wide variety of genes Pulling genomic...

Scientists show that when done right, partial elimination of microglia, the immune cells of the brain, lowers age-related inflammation and cellular senescence [1]. Aging makes microglia bitter Brain health is of utmost importance for geroscientists, since the brain is the one organ that cannot be replaced, and microglia are the brain's resident immune cells. Reacting...

A team of researchers publishing in Aging have shown that resveratrol reduces inflammation and partially restores function in a rat model of spinal injury. In line with previous research This is far from the first study that aimed to use approaches associated with aging research in order to spur regeneration. For example, we have previously...

Publishing in Science Advances, a team of researchers has described how a scaffold containing genetically engineered induced pluripotent stem cells (iPSCs) can reduce symptoms in a mouse model of rheumatoid arthritis. The advantage over current drugs Rheumatoid arthritis (RA) is currently treated through drugs that often suppress the immune system as a side effect [1]....

Researchers, publishing in the journal Aging, have discovered that a protein called hedgehog alleviates the tissue-specific, age-related inflammation of the microglia, the maintenance cells of the brain. The aging differences between tissue types To begin this research, the team first performed a gene expression analysis on four different types of murine macrophages: bone marrow-derived macrophages...

Epigenetic clocks have become a mainstay of longevity research over the past few years, with new clocks regularly being established for different species and tissues as well as promising research that uses and builds on these clocks. An international research team has recently created a different kind of clock, an inflammatory aging clock that predicts...