Tag: Fertility

Researchers publishing in Aging have found that rapamycin, a molecule thoroughly researched for its effects on metabolism, improves the viability of egg cells (oocytes) grown in vitro. Another approach towards a known problem Decreased fertility in women occurs much more rapidly than other aspects of aging, and advanced maternal age has a substantial impact on...

Scientists have discovered that immature oocytes maintain their youth by shutting down one of the protein complexes that produce energy in mitochondria [1]. Live slow, stay young Every female is endowed with a finite number of oocytes that form before birth, then reside in the ovaries in a dormant state until maturation and release. Oocytes...

A group of researchers has documented in Aging that Epitalon, a synthetic peptide made of four amino acids, slows the aging of egg cells (oocytes) after ovulation. Aging makes fertilization difficult Oocyte aging is well-known to lead to fertilization deficiencies and a host of other problems that are visible in the cells themselves, including abnormalities...

A large-cohort population study from Denmark has linked metformin to a 40% increase in the risk of birth defects when taken by fathers during the spermatozoa development period [1]. A drug linked to longevity Metformin is an anti-diabetes drug that drew geroscientists' attention after studies had shown that it reduces all-cause mortality and alleviates diseases...

Scientists have found that long-term supplementation with NMN, an NAD+ precursor, dramatically slows reproductive aging in mice by improving mitochondrial function and alleviating senescence [1]. Reproductive aging affects women relatively early in life, but like other types of aging, this one has been considered normal until recently, and no serious attempts have been made to...

A study conducted at the Institute of Reproductive Medicine in South Korea has shown that the protein expressed by growth-associated gene 6 (GAS6) ameliorates age-related decline in egg cells (oocytes). A protein with many functions Like many other proteins, the GAS6 protein serves multiple functions. It is associated with cellular proliferation, immunity, platelet activation, and...