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Tag: Fertility

Image of an oocyte
September 24, 2020
According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that NMN treatment can restore the metabolic balance in aging mouse oocytes, rescuing fertility. Defective eggs Although malfunctioning of mitochondria and the accumulation of mutations in mitochondrial...
Egg cell
June 11, 2020
Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it must divide to create a human being, the oocyte is the largest cell in the human body, and it contains far more mitochondria than any...
Pregnant rat
February 24, 2020
A new mouse study published in Cell Reports has shown that a metabolic precursor of the coenzyme NAD+ rejuvenates oocytes (egg cells), restoring fertility [1]. The oldest cells In humans, female fertility begins to decline near the end of the third decade of life, long before other markers of aging appear. This age-related decline is...