March 23, 2023
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the Lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which looked at the effects of prolonged fasting on human macrophages and how metabolites from that fasting increased median lifespan in Caenorhabditis elegans. Abstract Periodic prolonged...
December 06, 2022
Scientists from Singapore have found that intermittent fasting alleviates damage incurred by chronic cerebral hypoperfusion, the impaired blood flow to the brain that is thought to be a cause of age-related dementia [1]. Why intermittent fasting? Back in the early days of geroscience, caloric restriction was the first intervention to substantially increase lifespan in lab...
December 05, 2022
Researchers publishing in Nature Communications have determined that interventions that extend lifespan in mice may not have significant effects on the processes of aging. Improvement is not the same as slowing decline The researchers begin this paper by noting that previous studies have outlined a broad variety of dietary, environmental, and genetic factors that are...
October 21, 2022
Scientists have shown that both high-intensity interval training (HIIT) and time-restricted eating improve metabolism in healthy overweight women, with their combination providing the biggest effect [1]. Which one is better? Good dietary habits and physical activity are currently our best options for living longer and healthier lives. In recent years, two interventions have been gaining...
May 17, 2022
In a new study published in Science, researchers show that caloric restriction and time-restricted feeding have an additive effect on lifespan in mice [1]. A well-known intervention Caloric restriction is considered the first intervention to reliably show that aging is a malleable phenomenon. The first trials were conducted on rats back in the 1930s and...
March 23, 2022
A cohort study that was published in BioMed Central by Dr. Alsayyari and colleagues examined fasting on acute kidney injury incidence [1]. Background Fasting during the month of Ramandan is a obligation in Islam with exceptions, such as for chronic illness that has a poor prognosis or is uncontrolled [2]. Our prior articles discuss the...
