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Tag: Transcriptomics

Centenarian
Scientists have discovered a possible mechanism that protects extremely long-lived people from aging [1]. Protected persons A few days ago, news came of the death of the oldest person in the world (and the oldest ever to have her age indisputably confirmed), 119-year-old Kane Tanaka from Japan. People who live past 100 or 110 years...
Cell targeting
An open access study published in iScience has discussed the development of senolytics to target particular genes that are upregulated in cellular senescence. Understanding senescence, cell by cell In our earlier interview with Simon Melov of the Buck Institute, the lead researcher of this paper, Dr. Melov, explained his lab's focus on single-cell sequencing. As...
Treasure Map
As explained in a paper published in GeroScience, researchers have used spatial transcriptomic analysis to show the inflammatory nodes that are caused by brain cells undergoing senescence. What is spatial transcriptomic analysis? Spatial transcription analysis isn't a full 3D view of an entire brain. Rather, it is based on a series of slides of mouse...
Mouse clock
A new preprint on bioRxiv shows how researchers have developed transcriptomic, cell type specific aging clocks from the regenerative zones of mouse brains [1]. Measuring age at the level of a single cell Aging is multi-faceted and difficult to quantify. While chronological age is straightforward, it doesn’t necessarily capture the underlying biology, as individuals naturally...
Gene transcription
Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64 and older [1]. Background Recently, we discussed misconceptions from the media on research developing on HBOT for age reversal. The Sheekey Science Show discussed both...
Omics
The latest research in Aging Cell has brought to light new insights into the biology of aging and associated therapeutic candidates. What is multi-omics? "-omics" refers to branches of molecular biology that attempt to characterize and/or quantify their components in totality, often using recently developed big data technologies. For example, genetics is the study of...