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Tag: Senolytics

Clinical Trial
A team of researchers, including Dr. James Kirkland of Mayo Clinic, has published a review of the ongoing efforts of researchers to clear senescent cells through senolytics. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part;...
Research fundamentals
Two of the most prominent experts in the field have published a review of cellular senescence in the context of metabolism, and we bring you the highlights [1]. We rarely cover review papers, but when Cristopher D. Wiley and Judith Campisi, two of the most prominent experts on senescent cells, publish a review on senescence...
Erase bad cells
A group of researchers has developed a delivery system that identifies senescent cells and injects them with a deadly compound. This offers a potential solution to the problem of targeted delivery of senolytics [1]. Cellular senescence has been implicated in numerous aging-related disorders, including fibrosis, diabetes, cancer, and Alzheimer's. Today, senolytics, drugs that remove senescent...
Spinal Disc Degeneration
A group of researchers has found that early long-term treatment of mice with the popular senolytic duo dasatinib and quercetin alleviates symptoms of intervertebral disc degeneration, a major age-related cause of disability [1]. Age-related disease with early onset Conventional wisdom says that our spines just were not built to last for as long as humans...
Removing senescent cells with senolytics may reverse some aspects of aging.
In this article we will take a look at senolytics and how they have the potential to reverse some aspects of the aging process. Senescent cells and aging As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissues of which they...
Capers are high in quercetin which may help slow down aging.
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. We take a look at this natural compound and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of water-soluble plant compounds. Flavonoids are not created by the body...