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Tag: Senolytics

Scientific Announcement
Leading the pack is never easy, but today, UNITY Biotechnology is back with some positive news for senolytics. Being first is not always easy UNITY Biotechnology is a company that has been developing senolytics for the removal of senescent cells, which accumulate with age, drive chronic inflammation, and spur various age-related diseases. Why we Age:...
Strawberries
We take a look at the popular supplement fisetin and see how it stacks up as a potential anti-aging supplement. What is Fisetin? Fisetin is a plant polyphenol and part of the flavonoid group in the flavonol sub-category.  It is present in many trees and plants, including Eudicotyledons, Acacia greggii, Quebracho colorado, Rhus cotinus, and...
Oisin Logo
Today, Oisín Biotechnologies, a well-known developer of senolytics, drugs that destroy harmful senescent cells, has announced that it has more than doubled its total funding through an oversubscribed round. This has taken its total funding from $4.5 million to $9.5 million. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent....
Missing pieces of the brain
A new study by a team of researchers, including Dr. Kirkland of Mayo Clinic, shows the effect of whole-body senolytic treatment on the health and function of the brain. This follows up on previous Mayo Clinic research led by Dr. James Kirkland. That experiment treated mice with a combination of the cancer drug dasatinib and...
The robot eye of AI
A group of scientists has created a neural network that identifies senescent cells by their morphology and can be used for senolytic drug screening [1]. Image recognition is a showcase triumph of artificial intelligence. While this problem was considered extremely hard to crack in previous decades, algorithms have now exceeded human abilities in multiple cases....
The Sheekey Science Show on fisetin
In this video, the Sheekey Science Show explores fisetin, a flavonoid that is found in strawberries and shown to have senolytic effects. This compound, a polyphenol like resveratrol and quercetin, has been shown to somewhat activate SIRT1, which enhances longevity, while eliminating harmful senescent cells in mice, as proven by the reduction of cells that...