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Tag: Senolytics

June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age, increasing numbers of your cells enter into a state...
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What are senescent cells? As you get older, more and more of your cells enter into a state known as cellular senescence. Senescent cells no longer...
June 05, 2020
Don’t let your birthday get you down and remind you that you are getting older; there are plenty of reasons to be cheerful about the future and your place in it, especially as science is now turning its attention to aging. Another trip around the sun So here I am again, another birthday just gone...
May 29, 2020
Could a vaccine approach to removing harmful senescent cells that accumulate with age be an alternative to senolytic drugs, which destroy them? Some researchers certainly believe it might and have published a new mouse study showing just that. What are senescent cells? As you age, increasing numbers of your cells enter into a state known...
May 22, 2020
At this moment in history, the study of the biology of aging frequently brings us new discoveries, and today is no exception. Researchers have discovered a new drug that appears to destroy lingering senescent cells, and it achieves this without using any of the previously known mechanisms or pathways normally associated with inducing cell destruction....
May 12, 2020
A group of scientists from China has successfully created an effective senolytic prodrug that targets the enzyme β-galactosidase [1]. This prodrug, called SSK1, has demonstrated impressive results across various cell types and advantages over some existing senolytics. Cellular senescence is a phenomenon in which cells stop dividing and supporting the tissues of which they are...