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Tag: Neurons

August 06, 2020
A new study published in Cell Stem Cell has shown how astrocytes, glial cells that perform multiple critical functions in the brain, can become neural stem cells (NSCs) in response to injury. Astrocytes' normal functions The term 'astrocyte', meaning star-shaped cell, refers to a very heterogenous population of cells that perform maintenance, management and constructive...
January 20, 2020
Scientists at Scripps Research have developed a new screening platform that has allowed them to identify a new set of compounds that appear to have a potent protective effect on the mitochondria of brain cells, helping these cells to defend against the kinds of stresses encountered during Alzheimer's disease and other neurodegenerative conditions. Improved screening...
June 05, 2018
Thanks to a new technique, researchers from the Salk Institute's Gage laboratory have shown that impaired energy production might be a reason why human brains are susceptible to age-related diseases in the first place [1]. In particular, Salk scientists observed that induced neurons (iNs) obtained from fibroblasts of older individuals had dysfunctional mitochondria and therefore...
March 28, 2018
In a paper published on March 15, 2018, in the journal Science, Stanford researchers led by Dr. Dena Leeman showed that intracellular protein aggregates accumulate within the lysosomes of neural stem cells that were previously thought not to suffer from this problem [1]. Intracellular waste disposal 101 Dysfunctional proteins and organelles within a cell constitute...