September 26, 2022
A paper published in Cell Metabolism has reported on a metabolic shift in neurons derived from patients with Alzheimer's disease, showing that they express a cancer-like phenotype [1]. Induced neurons Rather than attempting to harvest live neurons from Alzheimer's patients, the researchers chose to create induced neurons (iNs) from the fibroblasts of these patients, comparing...
July 06, 2022
A new study published in Stem Cell Research and Therapy has shown that rejuvenating the astrocyte niche in the aged brains of mice leads to improved nervous system function at both the cellular and organismal levels [1]. A glia-centric approach In brain aging, neurons are quite literally only half of the story; the other half...
October 25, 2021
A team of researchers publishing in Aging have shown that resveratrol reduces inflammation and partially restores function in a rat model of spinal injury. In line with previous research This is far from the first study that aimed to use approaches associated with aging research in order to spur regeneration. For example, we have previously...
October 22, 2021
Researchers have identified an important mechanism of neurodegeneration that may be useful in treating age-related diseases such as Alzheimer’s and dementia [1]. These neurons must die Age-related neurodegenerative diseases, including Parkinson’s and Alzheimer’s, have become more prevalent mostly because of the successes of modern medicine. Today, more people become old enough to fall prey to...
September 03, 2021
Cognitive decline and neurological aging may involve a peptide known as adropin, according to new research. The identification of this link offers a new perspective on the aging brain and points to novel potential therapies. A newly discovered metabolic neuropeptide The adropin protein is encoded by the Energy Homeostasis Associated (ENHO) gene, and as the...
August 23, 2021
Researchers publishing in Aging have found that stresses, both biological and in daily life, harm one of our fundamental abilities to correctly process what's going on around us. What is sensory gating? Sensory gating is the brain's ability to filter out irrelevant stimuli after the first time it experiences them. It reflects our ability to...
