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Tag: Genomic Instability

In vitro fertilization
Researchers publishing in Aging have found that rapamycin, a molecule thoroughly researched for its effects on metabolism, improves the viability of egg cells (oocytes) grown in vitro. Another approach towards a known problem Decreased fertility in women occurs much more rapidly than other aspects of aging, and advanced maternal age has a substantial impact on...
Bowhead whale
A preprint published in bioRxiv has partially explained the lifespan of the bowhead whale through its duplication of CDKN2C, which regulates how cells divide. Peto's paradox It would be logical for longer-lived animals to be more susceptible to cancer than shorter-lived animals over time, as they have longer to develop the mutations that lead to...
Mutant cell
A preprint published in bioRxiv has shown the mechanisms by which cancer handles the protein dysfunction brought about by its own mutational load and how these mechanisms are different from ordinary proteostasis machinery. A highly variable burden Previous research has shown that tumors vary widely in their numbers of mutations. Some cells in a single...
Skin aging
In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental) factors that drive skin aging. While the environmental factors that affect the rate of skin aging, such as sun exposure and smoking, can be controlled,...
The NOVOS company logo in orange
NEW YORK - June 15, 2022 - NOVOS, a company that develops science-based products to slow down aging, announced results of two studies demonstrating that the combination of ingredients in its products, NOVOS Core and NOVOS Boost, protect against DNA damage and cellular aging (senescence). A study found that a combination of the 12 ingredients...
Rectal cancer
Researchers publishing in the New England Journal of Medicine have been able to completely eliminate stage 2 and 3 rectal tumors with a single monoclonal antibody drug [1]. Therapy comes with a price If we leave out skin cancers, colorectal cancer is the third most commonly diagnosed cancer in the US. According to the American...