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Tag: AKG

Backwards Clock
A commercially available alpha-ketoglutarate-based supplement has been shown to roll back biological age by 7 years on average in a retrospective human study [1]. Live slower, die later Though metformin and rapamycin are getting most of the attention in the longevity field today, alpha-ketoglutarate (AKG) has emerged as another candidate longevity drug. These three molecules have...
AKG may be a useful supplement for slowing down aging.
Alpha-ketoglutarate (AKG) has long been a popular sports supplement and is often used in the bodybuilding world, but interest in this molecule has now reached the aging research field due to its central role in metabolism. What is alpha-ketoglutarate? AKG is a naturally occurring endogenous intermediary metabolite and part of the Krebs cycle, which means...
A picture of the Alpha-ketoglutarate molecule
Alpha-ketoglutarate (AKG) is a popular dietary and sports supplement frequently used in the bodybuilding world, but interest in this molecule has more recently reached the aging research field for its potential to slow down aging. AKG is a naturally occurring endogenous intermediary metabolite, which means that our own bodies create it, and is part of...
The Sheekey Science Show
As we reported yesterday on Lifespan.io, the common supplement alpha-ketoglutarate has been shown in a rodent study to combat osteoporosis, the age-related loss of bone tissue caused by an imbalance between bone-building and bone-destroying cells. Today, we present a related video from the Sheekey Science Show, a popular science show that often discusses aging and...
Osteoporosis Hip
Research on rodents shows that alpha-ketoglutarate could be an effective way to treat or even prevent osteoporosis [1]. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur by giving our...
Dr. Brian Kennedy thumbnail
At Ending Age-Related Diseases 2020, Dr. Brian Kennedy of the National University of Singapore discussed the aging population of Singapore, the need for comprehensive healthcare, alpha-ketoglutarate (AKG) and its effects against frailty in mice, ongoing trials of ketoglutarate in humans, spermidine against obesity, the role of biomarkers, and the importance of keeping people well rather...