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Red Blood Cells as Biomarkers of Aging
The advent of artificial intelligence and its application to the study of aging and longevity took a giant leap forward in 2013 with the development […]
A Light-Sensitive Drug to Remove Senescent Cells
Research published in Nature Aging has shown that a photosensitive senolytic drug can be used to selectively remove senescent cells, slowing functional organ aging in mice. A problem of delivery […]
Ultrasound Rejuvenates Senescent Cells Through Autophagy
In a preprint paper, the researchers have shown that low-frequency ultrasound treatment decreases senescence and improves the physical performance of aged mice [1]. Mechanical approach Cellular senescence, the inability […]
Rejuvenation Roundup January 2023
As 2023 continues, so does new research into rejuvenation, regeneration, and restoration. Let’s see what’s been done to reverse age-related diseases in January. LEAF News Team […]
Lifespan News – Tearing Cells
On this episode of Lifespan News, Emmett Short focuses on a recently published paper in which senescent cells tear off portions of their membranes, leaving them attached to […]
VitaDAO Closes $4.1 Million Fundraising Round
VitaDAO, a decentralized organization funding early-stage longevity research and biotech start-ups, has announced the successful closing of a $4.1 million funding round dedicated to financing future longevity projects and furthering its […]
Longevity-Associated Allele Protects Heart Function in Mice
Scientists have shown that a longevity-associated variant of the BPIFB4 gene protects cardiovascular health, including when introduced by viral vectors [1]. All […]
Gene Therapy for Heart Regeneration in Living Animals
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE of life This study is […]
New Way to Help Aging Cells Produce Collagen
Scientists have demonstrated that extracellular vesicles loaded with mRNA coding for collagen production can be easily produced and delivered into aging fibroblasts in vitro and in vivo, […]
Brain Aging on a Small, Physical Level
A new publication in Nature Aging has explained a great deal about aging of the neurovascular system, showing where and how […]
Eric Verdin on the Buck, Nutrition, and Ketosis
Six years ago, Dr. Eric Verdin, already a highly acclaimed veteran geroscientist, was catapulted to the forefront of the field when he agreed to lead the Buck Institute for Research on Aging (or […]
New Year, Same Goal to End Age-Related Diseases
The new year is well underway, and we have been our usual busy selves. Join us for the first editorial of the year, and […]
Lifespan News – Mediterranean Diet Against Obesity
In this episode of Lifespan News, Emmett Short discusses the well-known, longevity-associated Mediterreanean diet and how a variant can promote weight loss. Script The Mediterranean diet, rich in olive oil, vegetables, legumes, […]
Caloric Restriction Does Not Extend Lifespan in Every Model
In a preprint paper, researchers have evaluated the effect of caloric restriction on two long-lived planarian species in various environments that mimic the stochasticity […]
Partial Reprogramming Extends Lifespan in Old Mice
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We […]Journal Club January 2023
The journal club returns on Tuesday 31st January at 12:00 Eastern on our Facebook page with host Dr. Oliver Medvedik. We are looking at a preprint this time where partial reprogramming factors were used to reverse some aspects of […]
Longevity Investors Lunch at Davos
A Longevity Investors Lunch hosted by Maximon, Longevity Investors Conference, and Biolytica has been hosted at a satellite event of the well-known Davos conference. The press release is included here. Longevity stays in the limelight on […]
NMN Reduces Metastasis in Difficult Breast Cancer Model
In a new paper published in Nature, scientists have found that raising NAD+ levels via supplementation with nicotinamide mononucleotide (NMN) activates SIRT1 to dampen metastasis in mouse TNBC models [1]. A double-edged sword NAD+ is a ubiquitous […]
Open Longevity Foundation Announces Open Genes Database
Open Longevity Foundation has announced Open Genes, a database of longevity-associated genes and a tool for future anti-aging therapy development. The full press release is included here. […]
Allogeneic CAR-T Cells Complete Phase 1 Trial
The results of a Phase 1 clinical trial of allogeneic CAR T cell therapy against multiple myeloma have been published today […]
Senescent Cells Leave Fragments Attached to Other Cells
In a preprint paper, scientists have reported that senescent cells transiently adhere to neighboring cells, and, upon departure, leave in place large membrane-enclosed fragments of themselves [1]. Mysterious […]
Exploring the Biological Aging Advice in “Younger You”
Dr. Kara Fitzgerald’s new book provides an evidence-based approach to diet and lifestyle that aims to reduce your biological age. Beginning with […]
Introducing A Longevity Hackathon for Accelerating Research
The latest hackathon event, LongHack, hosted by the VitaDAO team beginning today and continuing over the weekend, will focus on discovering new approaches to longevity science and inspiring new initiatives in the […]
The APOE4 Gene Is Associated With Worse Stroke Outcomes
Researchers publishing in Aging have found that there is a correlation between the APOE4 gene and poor outcomes after ischemic stroke. An allele with a long and sordid history Other than its well-known association with Alzheimer’s disease, the […]
Selfish, Reckless, Satanic: Life Extension in Movies
In the much-awaited sequel to the movie Avatar, there is a passing, peculiar mention of life extension. This mention, as can be expected, is negative. In the movie, the greedy, nature-destroying humans […]
Questioning the Usefulness of Model Organisms
In a new review paper published in GeroScience, the researchers explored the translatability of anti-aging interventions across species and received somewhat alarming results [1]. Necessary, but not […]
The Relationship Between ApoE and Alzheimer’s
Alzheimer’s disease is the most typical form of dementia. It is a progressive disease that begins with mild memory loss, leads to […]
The Microbiome Might Affect Motivation for Exercise
Scientists publishing in Nature have found that compounds produced by some types of gut bacteria can influence dopamine levels in the brain and, as a result, might […]
Lifespan News – NMN Optimal Dose
This episode of Lifespan News focuses on a recent study showing that NMN has positive effects on walking distances and suggests an optimal […]
NMN Alleviates Silicate Lung Injury in Mice
A new paper published in Nutrients shows that the well-known NAD+ precursor NMN alleviates lung injury caused by silicate inhalation in wild-type mice. An antioxidant […]
