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Plasmalogens Alleviate Age-Related Cognitive Decline in Mice
Scientists have learned that plasmalogens, obscure but important lipids, serve as a mediator of neurogenesis and synaptic health and can reverse age-related cognitive decline in mice [1]. Plasmalogens and membranes Plasmalogens are a subtype of […]Visually Identifying Senescent Cells with an Algorithm
A team of researchers publishing in Aging has developed a method of identifying senescent cells through their physical morphology, potentially making future senescence research much easier. Senescent […]Blood Pressure Linked to Dementia, Mortality in Older People
A recent study from the Journal of the American College of Cardiology, conducted by Dr. Wuxiang Xie and colleagues, examined the association of blood pressure with cognitive decline, dementia, and […]Lithium Use Might Lower Risk of Dementia
A study published in Plos Medicine has shown that lithium decreases the risk of developing dementia and some of its subtypes, including Alzheimer’s disease and vascular dementia [1]. Enigmatic […]Announcing LessDeath.org and Longevity Summer Camp
LessDeath.org is organizing an educational retreat from July 20 to 24 in Nevada City, California, featuring many luminaries from the longevity world and focusing on community building […]How to Lose Weight Fast and Why You Shouldn’t
Maintaining a healthy weight is a sensible strategy for staying healthy and trying to slow down aging. However, a lot of people try to lose weight fast through crash diets and extreme calorie cutting. This is a bad […]Young Cerebrospinal Fluid Improves Memory in Mice
Scientists have found that infusing old mice with cerebrospinal fluid obtained from young mice improves their memory by increasing proliferation and differentiation of […]Designing a DAO: Insight from the VitaDAO Team
DAOs are relatively new forms of organizations that use blockchain technology to function in a decentralized, autonomous way. Like traditional organizations, they serve a variety of functions, such as […]How DAOs Balance Decentralized Decisions and Efficiency
It’s often said that too many cooks in the kitchen can spoil the soup. Transferring this notion of too many voices to the DAO, […]Lifespan News – CBD and Autophagy
On this episode of Lifespan News, Ryan O’Shea discusses how CBD promotes autophagy, our cells’ ability to clear out damaged components. Script Scientists […]Biological Aging Fluctuates with Stress
A preprint published in bioRxiv has demonstrated that the second-generation aging clocks PhenoAge, DunedinPACE, and GrimAge show increased but reversible age acceleration in mice and people exposed to significant stress. What clocks are for As the researchers remind us, […]“The Perfect Diet” May Increase Lifespan by 13 Years
Scientists from Norway have built a model that predicts the effect of various dietary changes on human lifespan [1]. Diet is obviously a major health factor, but quantifying its impact is not easy. Since it is all but impossible to […]Journal Club May 31st at 12:00 Eastern
Journal Club returns May 31st at 12:00 Eastern live on the Lifespan.io Facebook page. Dr. Oliver Medvedik will be exploring a recent paper where researchers showed that transfering fecal microbiota from young to old mice reversed some […]Fecal transfer between young and aged mice reverses hallmarks of aging
The Journal Club returns May 31st at 12:00 Eastern live on the Lifespan.io Facebook page. Dr. Oliver Medvedik will be exploring a recent paper where researchers showed […]The Role of Mitochondrial Antioxidants in Longevity
A study published in Redox Biology has reported that the upregulation of thioredoxin, a fundamental part of mitochondrial defense against reactive oxygen species, is associated with longevity in mutant C. elegans worms. Free radicals, revisited The free […]Rejuvenation Startup Summit to Be Held in Berlin
Another aging conference has been announced in Berlin, Germany. In this event, the Forever Healthy Foundation will be focusing on […]Reprogramming Cells with Vittorio Sebastiano of Turn.bio
Vittorio Sebastiano is an Associate Professor (Research) of Obstetrics and Gynecology at Stanford University and one of the most prominent scientists in the emerging field of cellular reprogramming. He is also co-founder and […]Decentralized Science Event Happening May 23-24 in Berlin
The future of research funding is changing, and DeSci is set to play a key role in that. Focusing on how […]FOXM1 Induction Extends Lifespan in Mice
In a new study published in Nature Aging, researchers have shown that inducing a truncated FOXM1 gene extends lifespan in both […]Discussing Crowd Funded Cures with Savva Kerdemelidis
We have written extensively about VitaDAO, a collective dedicated to community-governed, decentralized drug development. Probably the fastest and cheapest way to get geroprotective drugs to the market is by repurposing existing drugs, such as rapamycin, metformin, and acarbose. […]Caloric Restriction, Feeding Times Lengthen Mouse Lifespan
In a new study published in Science, researchers show that caloric restriction and time-restricted feeding have an additive effect on lifespan in mice [1]. A well-known intervention Caloric restriction is considered the first intervention to […]The Development of Glowing Pluripotent Cells
A team of Chinese researchers has described a novel method of illuminating pluripotent stem cells in a paper published in Aging. How and why Using a lentivirus, the researchers genetically engineered mouse embryos to express green fluorescent protein (GFP) when […]BioAge Is Developing Novel NLRP3 Inhibitors
BioAge Labs is developing a class of compounds that have been shown to inhibit the NLRP3 protein, which has been linked to all-cause mortality, in mouse models and human cells. These compounds can be taken orally and cross the blood-brain […]Arguing that Life Extension is Not a Priority
Arguing that other issues should get priority over tackling aging is an all-too-common reason for not developing life extension technology. We cannot have life extension unless […]João Pedro de Magalhães on Reprogramming and Aging Theories
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He […]Life Extension Is Another Form of Freedom
Freedom is a big deal for our society. We want freedom of speech, political freedom, freedom of the press, religious freedom, […]Using an Endemic Virus as a Gene Therapy for Life Extension
In a study printed in PNAS, researchers have shown that telomerase reverse transcriptase (TERT) can be given to cells in […]Walking Pace Correlated with Increased Telomere Length
Publishing in Nature Communications, Dr. Tom Yate, Dr. Neliesh J. Samani, and colleagues used data from approximately 400,000 people in the UK Biobank in order to examine the relationship between walking pace and telomere length. Previous evidence suggests that increased […]Lifespan News – Plastic Nanoparticles
Hosted by Ryan O’Shea, this episode of Lifespan News is on how plastic nanoparticles might lead to at least one hallmark of aging being accelerated. Script Studies show that everyday objects […]Ending Age-Related Diseases 2022 Early Bird Tickets on Sale!
This year sees us hosting the fifth Ending Age-Related Diseases conference, and once again we are bringing you four action-packed days of aging […]
