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Music Therapy for Treating Alzheimer’s Disease
The authors of a new review have analyzed randomized controlled trials that evaluated the impact of music therapy on the cognitive functions of people with Alzheimer’s [1]. Music […]Isoleucine Restriction Boosts Lifespan in Mice
A new study reports a massive 33% increase in median lifespan in male genetically heterogeneous mice following prolonged isoleucine restriction [1]. Not all calories are created equal Caloric restriction is the most powerful life-extending intervention in […]Mammals Accumulate Epigenetic Noise With Age
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We […]B12 Is a Limiting Factor for Induced Cellular Plasticity
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be […]Journal Club Nov – B12 and Cell Plasticity
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the Lifespan.io Facebook channel and hosted by Dr. Oliver Medvedik. This month we […]Predicting a Species’ Longevity Through Epigenetics
A preprint study published on bioRxiv discusses how a species’ maximum lifespan can be predicted by its epigenetics, showing that these differences are largely unaffected by interventions. Differences and similarities in […]Aging Might Blunt the Effects of Fasting
Scientists have found that in killifish, old age is associated with a dampened response to fasting and identified the protein that might be […]Some HIV-Fighting Drugs May Also Fight Aging
Publishing in Ageing Research Reviews, a team of researchers including Vera Gorbunova has described how a class of drugs originally used to treat HIV might be used to affect some of the hallmarks […]Dual-Purpose Molecular Targets for Cancer and Aging
A new study published in Aging Cell applied an artificial intelligence target discovery platform to aid in identifying potential dual-purpose […]Young People More Vulnerable to Atherosclerosis Risk Factors
A new study suggests that increases in LDL cholesterol and systolic blood pressure elevate the risk of atherosclerosis progression more in younger than in older people. The good news is that this can be reversed [1]. Creeping atherosclerosis Atherosclerosis […]A Lack of Skin Collagen May Encourage Cancer Growth
A new paper published in Nature has described how the aging extracellular matrix makes it easier for cancer to grow. When cancer is skin […]An Anonymous Longevity Enthusiast Unmasks Himself
A prolific anonymous poster who became popular in the longevity community has revealed his identity, and other longevity luminaries have chimed in. The anonym Anonymity is seldom practiced in […]Pushing Forward on Understanding Cellular Decline
Researchers publishing in Nature Aging have investigated one of the core biological reasons behind the decline of stem cells’ ability to proliferate. Heterochromatin and euchromatin The genetic […]Plant-Based Alternatives Are Associated With Less Disease
A new meta-analysis has found that in many cases, switching from an animal product to a plant-based alternative is associated with less cardiovascular, diabetes, and all-cause mortality risk [1]. Supplant with […]Senolytics May Work Against Long COVID in the Brain
A new publication in Nature Aging has used organoids and model mice to discover that senolytics may be effective treatments for neurodegeneration caused by long COVID. A link between COVID-19 and cellular senescence Post-acute infection syndromes […]How Rejuvenation Benefits Children and Families
Rejuvenation biotechnology promises several benefits for individuals, but this technology, if thorough and widely adopted, would benefit larger groups of people, including your friends and family. If you […]Why Rejuvenation Biotechnology Could Benefit You
Part of our job at Lifespan.io is to inform everyone that rejuvenation biotechnologies need to happen, and we’re doing our best to make them happen as soon as possible. […]Promoting Health and Longevity Through Diet
A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, […]A Phytomolecule Improves Tendon Regeneration in Rats
A new study has identified a molecule found in Saposhnikovia root as a potent mediator of tendon regeneration in rats. The results were also replicated in human cells [1]. Aging does not spare […]The Societal Benefits of Rejuvenation Biotechnology
Rejuvenation biotechnologies promise to bring benefits to ourselves and the people close to us. Most people have no difficulty acknowledging these benefits, […]Targeting Metabolism to Protect Against Stroke
Japanese researchers publishing in Aging have described how improving the AMPK metabolic pathway improves outcomes in a rat model of stroke. Targeting metabolism directly This paper begins with a look back at previous research on the focus of […]Mediterranean, Keto, and Plant-Based Diets Vs. Cancer
A new review summarizes what we know about the Mediterranean, keto, and plant-based diets and their effects on cancer risk and progression [1]. Diet matters Since the War on […]Cells Regularly Donate Mitochondria to One Another
In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies. A relatively […]Olive Oil Fights Cognitive Decline in Clinical Trials
In a recent review published in Frontiers in Nutrition, the researchers reviewed studies linking olive oil consumption to cognitive performance [1]. Dietary interventions to improve cognition As […]Rejuvenation Startup Summit 2024 Announces First Speakers
The Forever Healthy Foundation is pleased to announce the first set of speakers for its Rejuvenation Startup Summit 2024. The Rejuvenation Startup Summit (Berlin, May 10-11, 2024) is a vibrant networking event that brings together startups and members of the Longevity venture capital/investor […]Lifestyle Interventions Against Cellular Senescence
A new review summarizes our knowledge about lifestyle interventions, such as exercise, healthy diet, and good sleep, that can possibly reduce cellular senescence [1]. What do we do with […]Tweaking the Growth of Stem Cells for Better Therapies
Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, […]Alcohol Consumption Increases Epigenetic Age Acceleration
A new study has found that higher levels of long-term alcohol consumption are associated with a larger gap between the person’s biological and chronological age, but not in the young [1]. Don’t drink and age It […]Predicting Future Frailty with an Epigenetic Clock
An accepted manuscript in the Journals of Gerontology has described how a third-generation epigenetic clock is a predictor of future frailty. Are epigenetic and physiological […]Rejuve’s Longevity App Welcomes Peptide Bioregulator
‘Longevity’, an app designed to empower everyone to live longer, healthier lives, welcomes its latest partner, Peptide Bioregulator, a high quality […]