Insilico Medicine � USP1 Inhibitor (Cancer treatment)

This drug is a small molecule inhibitor of USP1, an enzyme that plays a significant role in the cellular response to DNA damage. The drug aims to inhibit USP1, leading to DNA repair inhibition, with potential implications for the treatment of tumors with homologous recombination and DNA repair deficiency. This compound has shown potent anti-survival activity in BRCA mutant tumor cells and is being explored both as a standalone therapy and in combination with PARP inhibitors.