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June 02, 2023
In one of the first studies of its kind, the popular senolytic combination, administered systematically for six months, produced several health benefits in these animals. Some effects were augmented by caloric restriction [1]. Coup de grâce for cells The combination of the drug dasatinib and the flavonoid quercetin, also known as D+Q, is one of...
May 31, 2023
Scientists publishing in Antioxidants have reported that increasing glutathione levels with GlyNAC, a supplement that combines glycine and cysteine, significantly reverses age-related cognitive decline in naturally aged mice [1]. GlyNAC vs oxidative stress Oxidative stress caused by reactive oxygen species (ROS) is known to be one of the upstream causes of aging and contributes to...
May 30, 2023
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Lai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a “pop-up city” conceived by the tech entrepreneur Vitalik Buterin, creator of Ethereum, and a group of like-minded people to facilitate co-living and collaboration in fields like crypto,...
May 26, 2023
Scientists have found that continuous oxygen restriction drastically extends the lifespan of progeroid mice, but the effect's mechanism remains a mystery [1]. Can less oxygen be better? Hypoxia is a condition in which an organism or an organ in the body does not receive enough oxygen. However, how much is enough, and whether we are...
May 23, 2023
Lifespan.io president Keith Comito presenting in Zuzalu. Photo: Arkadi Mazin While the format of this conference was rather conventional, the venue was anything but. It was held in Zuzalu, which can't be found on any map. Zuzalu is a unique “pop-up city” conceived by the tech entrepreneur Vitalik Buterin, creator of Ethereum, and a group...
May 19, 2023
Scientists studying people with autosomal dominant Alzheimer’s disease have found a genetic variant that is associated with decades of stalled onset [1]. The predictable Alzheimer’s Scientists still do not know what causes most cases of Alzheimer's, although certain genetic variants (most notably APOE4) have been shown to increase the risk of onset [2]. However, there...
