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Arkadi Mazin

Arkadi Mazin

About Arkadi Mazin

Arkadi is a seasoned journalist and op-ed author with a passion for learning and exploration. His interests span from politics to science and philosophy. Having studied economics and international relations, he is particularly interested in the social aspects of longevity and life extension. He strongly believes that life extension is an achievable and noble goal that has yet to take its rightful place on the very top of our civilization’s agenda – a situation he is eager to change.

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Articles from this author

DNA background
In a preprint showcased in bioRxiv, scientists have shown that a single cycle of partial cellular reprogramming can reverse multiple age-related changes in mice. Starting from a blank slate As was first shown in 2006 by a group led by Shinya Yamanaka, introduction of four transcription factors (proteins that influence gene expression) can make differentiated...
Neurons
Scientists publishing in Nature Aging have shown that telomerase reverse transcriptase slows neurodegeneration but not due to its telomere-building activity [1]. Chromosomes' bodyguards Why We Age: Telomere AttritionTelomeres are DNA regions located at the ends of a chromosome. Their normal length is 8-10 thousand base pairs, yet they consist of repetitions of a single sequence:...
Small food amount
In the first human trial of its kind, scientists showed that a fasting-mimicking diet can work synergistically with conventional therapies in cancer patients, altering their metabolisms and reshaping their immune systems [1]. What happens when you fast? Fasting is shaping up to be a powerful addition to clinical practice. It is not a panacea that...
Brian Kennedy
Dr. Brian Kennedy is a longevity heavyweight: a former President of the Buck Institute, currently a Distinguished Professor in the Department of Biochemistry and Physiology at the National University of Singapore, a co-editor of Aging Cell, and one of the researchers behind a recent study of alpha-ketoglutarate that resulted in winding back chronological age in...
Chest fibrosis
Scientists have created genetically engineered T cells that target activated cardiac fibroblasts in a transient manner, alleviating symptoms of cardiac injury [1]. HeartThe heart is a four-chambered organ located between our lungs. Blood is pumped by the heart through two loops, one to the lungs, oxygenating the blood, and the other out to the rest...
Synaptic Transmission
Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer's disease, still defy current treatment options, impeding attempts to increase human lifespan. According to the theory of competing risks, we cannot hope to meaningfully increase lifespan until all...