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Tag: Thymus

Happy mouse
By activating toll-like receptor 5, an important element of the innate immune system, scientists have increased lifespan and improved multiple health measurements in old mice, despite having started the treatment late in life [1]. TLRs and aging The immune system gets dysregulated with age, driving multiple age-related conditions [2]. It is manifested in higher tumor...
Small healthy meal
A new study published in Mechanisms of Aging and Development has shown that caloric restriction effectively restores T cell abundance in aged mice [1]. Is it really just about getting fewer calories? Caloric restriction has become a well-known anti-aging intervention, as it can reverse several hallmarks of aging and extend lifespan in different animal models....
Immune shield
A study published in Cell Reports shows how the thymus is stimulated to repair itself when dying thymocytes are depleted, paving the way towards novel methods of thymic regeneration. Cycles of involution, not a steady decline The researchers cite previous research showing that the thymus, despite being extremely sensitive to insults such as radiation and...
The human thymus
Publishing in Nature Communications' Cell Death Discovery, a team of Chinese researchers has discovered a reason for thymic involution, the age-related decline of the thymus. Adaptive Immune SystemThe adaptive immune system is a complex mechanism protects us from threats, including viruses and cancer. T cells and B cells are the backbone of this system.Read More...
X10 Thymic Rejuvenation
On this episode of X10, we talk about the TRIIM trial and question whether or not its participants have become biologically younger. Script If you're lucky, right now you're aging at a rate of one year per year—that is, your biological age is the same as your chronological age. If you are unlucky, you might...
rat on a petri dish
Recent research published in Nature Communications has regenerated a functional thymus in mice, making several other discoveries along the way [1]. A new sub-type of thymus cell emerges Although it is imperative to our immune health, the thymus is an under-studied organ that slowly disappears as we age. Its main function is to provide a...