February 05, 2024
A new study done in mice sheds light on how mental stress contributes to intestinal problems by altering microbiome composition [1]. Mind over matter Some experiences are not called “gut-wrenching” just metaphorically, as the brain can indeed influence gastrointestinal function in a myriad of ways. While most of them are adaptive, brain signals can also...
January 10, 2024
A new study published in BMC Psychiatry reviewed literature that links perceived stress during pregnancy with newborns' telomere length [1]. Lifelong impact of telomere length Telomeres are protective caps at the end of chromosomes. The shortening of the telomeres, which happens with each DNA replication cycle [2], is one of the Hallmarks of Aging. Why...
May 23, 2022
A preprint published in bioRxiv has demonstrated that the second-generation aging clocks PhenoAge, DunedinPACE, and GrimAge show increased but reversible age acceleration in mice and people exposed to significant stress. What clocks are for Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl...
February 10, 2022
A study published in Aging that studied the Northern Finland Birth Cohort of 1966 has found some interesting and counterintuitive results regarding work stress and accelerated epigenetic aging. Work stress is widely associated with premature death It is common folk wisdom that too much stress leads to a shorter lifespan, and this belief has been...
July 29, 2021
On this episode of X10, we talk about the concept of stress resilience, how our social lives are a factor in its development, and how it can be increased. Script The idea that stress affects aging is probably already familiar – it’s not exactly groundbreaking. Broadening and refining it would make it much more useful....
June 25, 2021
Many people dread finding their first greying hairs, which is often their first sign that aging is creeping up on them and that the fire of youth is starting to die down and smolder. To some readers, greying hair may seem to be a superficial issue; after all, it isn’t life threatening. However, in our...