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Tag: Stem Cells

Small meal
A review published in The Malaysian Journal of Medical Sciences has outlined what effects caloric restriction (CR) has on the development and differentiation of stem cells. Stem cells and their exhaustion The reviewers began by discussing stem cell exhaustion, a hallmark of aging and a common concern of aging research that we have covered extensively....
DNA Blood Cells
Researchers publishing in Cell Stem Cell have identified a protein that helps hematopoietic stem cells (HSCs) both in ex vivo cultures and in aging tissues. The problem with culturing cells Why we Age: Loss of ProteostasisThe loss of proteostasis is the failure of the protein building machinery of the cell and the accumulation of misfolded...
Fallopian Tube
The entire ovarian niche of mice can now be generated in vitro from stem cells, as a study recently published in Science shows [1]. The researchers then carried out the remarkable feat of fertilizing the generated oocytes and growing healthy, fertile offspring from them. This advance offers an invaluable model for investigating oocyte development and...
Invisibility
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients' immune response [1]. Help me help you Cellular therapies involve transplanting cells into a patient to replace the activity of malfunctioning or damaged cells. For example, cardiomycetes could be transplanted to...
Stem cell development
A new study published in the FASEB Journal shows how mesenchymal stem cells derived from adipose tissue (ADSCs) reverse some effects of aging in nearby cells. It's not the cells themselves, it's what they secrete The original and ongoing main purpose of stem cell therapies is to directly combat stem cell exhaustion: to replenish the...
Blood cells
Researchers have reversed the age-related decline in the function of hematopoietic stem cells (HSCs) in older mice using nicotinamide riboside. This success can make our blood more youthful and increase the effectiveness of stem cell transplantation [1]. There will be blood HSCs are the progenitors of all our blood cells. HSCs reside in the bone...