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Tag: Stem Cells

Dividing cell
Researchers publishing in Cell Stem Cell have found that the mitochondrial protein OPA1 is an integral, regulatory part of muscle stem cell activation, the process by which muscle stem cells proliferate and become active muscle tissue (myogenesis) [1]. Another piece of the puzzle We have recently reported on the effects of mitochondrial fusion and fission...
Scientists have improved the potential effectiveness of a stem cell therapy for osteoarthritis by targeting senescent cells [1]. Stem cell exhaustion and osteoarthritis Osteoarthritis is an age-related disease that affects joints by degrading cartilage. While not fatal in itself, osteoarthritis negatively affects mobility and quality of life, and it can decrease lifespan and healthspan. Several...
Strong mouse
In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple uses As multipotent stem cells, MSCs can differentiate into several different cell types, including fat cells, neurons, and bone cells [1]. The researchers point to...
Broken bone
A study published in the Journal of Clinical Investigation has reported that senescent cells are largely responsible for slow bone healing in aged animals and that senolytics, which remove these harmful cells, can speed bone regeneration. A brief outline of bone healing BoneBone tissue serves as the primary structural component of our bodies. It protects...
Chinese Licorice
Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous research on Licochalcone A has discovered that it has anti-inflammatory and anti-tumor effects [1], reduces obesity in mice [2], and protects against liver failure through...
Dividing stem cells
Researchers have found that hematopoietic stem cells lose function as they grow larger and that rapamycin can alleviate this effect [1]. When cells become obese When it comes to cells, size matters, with stem cells being on the smaller side [2]. Scientists have suspected for quite some time that this wasn’t a coincidence, but the relationship...