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Tag: Sarcopenia

Rejuvenate Biomed
Rejuvenate Biomed has recently concluded a clinical trial for sarcopenia. The results have shown “meaningful improvements in muscle strength, function and fatigue resistance”. What is sarcopenia? Sarcopenia is an age-related progressive loss of muscle mass and strength that affects many older adults. This decline in muscle mass and strength can greatly impact quality of life...
Intestine
In Aging, a team of researchers has outlined a possible relationship between low grip strength and compounds in the gut microbiome. The gut-muscle axis As these researchers note, previous work has described many of the various ways in which metabolism is related to age-related muscle dysfunction, including inflammation, oxidative stress, accumulation of advanced glycation end-products...
Wheelchair exercise
Today in GeroScience, researchers have published an analysis of a cohort study, concluding that adherence to physical activity recommendations can mitigate the increased mortality associated with disability. Simply being able to live In this paper, disability refers to impediments to the basic activities of daily living (ADLs), such as moving, dressing, showering, and eating. Disability...
Seaweed food
A recent publication in Aging and Disease describes human and animal research demonstrating improvement in the function and biomarkers of muscle tissue after Ishige okamurae extract supplementation [1]. The benefits of seaweed Clinical trials of seaweed consumption have reported beneficial health effects and protection against senescence-associated and metabolic diseases, such as cardiovascular disease, cancer, obesity,...
Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, potentially paving the way to a new system of therapies. When signaling is critical Many of the effects of stem cells can be traced back to the EVs,...
Mouse on wheel
Researchers associated with Rejuvenate Biomed and publishing in JCI Insight have conducted multiple experiments on a combination of metformin and galantamine in animal models. These preclinical experiments are intended to be a prelude to a human trial for sarcopenia. A debilitating disease with no pharmaceutical treatments The researchers start by discussing the well-known problem of...