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Tag: Parabiosis

Heterochronic Parabiosis
A preprint published on bioRxiv, whose authors include well-known biogerontologist Vadim Gladyshev, has shown us many interesting details of the effects that heterochronic parabiosis has on aging mice. An old concept studied in new depth Heterochronic parabiosis is the linking of the circulatory systems of young and aged animals. While the researchers note that this...
Electric brain
There has been a great deal of interest in the last few years in the potential regenerative properties of blood factors. This has led to two broad schools of thought: one in which there are regenerative factors in young blood that can be isolated, and another in which aged blood contains regenerative factors that cannot...
Blood cells
A team of researchers, including Dr. Tony Wyss-Coray, co-founder of Alkahest, has discovered that exposing young cells to aged blood causes their gene expression to become akin to aged cells. Signaling cells to act older We have known from the heterochronic parabiosis and plasmapheresis research performed by Dr. Irina Conboy's lab and similar work done...
On this episode of Journal Club, Dr. Oliver Medvedik presents a study from the Conboy research laboratory in which aged blood factors are diluted in the blood plasma of old mice using saline and albumin, which provides rejuvenative effects in brain, liver, and muscle tissues
The Journal Club returns this Tuesday, July 28th, at 12:00 PM EDT / 5 PM UK, with your host Dr. Oliver Medvedik, livestreamed to our Facebook page. We will be taking a look at the recent study published by Dr. Irina Conboy and her team [1]. The study showed that by replacing half of the...
By now, the race to discover regenerative factors present in blood has been underway for a number of years, with numerous researchers seeking a "secret sauce" in blood that has the potential to rejuvenate aged tissues and organs. A fork in the road It is clear from previous animal studies going back over a decade...