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Tag: Nicotinamide mononucleotide

July 23, 2020
There has been considerable debate around the age-related decline of NAD+, particularly regarding whether or not it occurs in humans as it does in other species, such as mice. Today, as part of a two-part special, we are going to be taking a look at some of the evidence for the age-related decline of NAD+...
May 25, 2020
A new study may shed some light on how aging and circadian rhythms may be linked by discovering a role for nicotinamide adenine dinucleotide (NAD+) in preventing the age-related disruption of circadian rhythms in mice. A circadian rhythm is an automatic process that regulates a cycle of behavioral changes and repeats roughly every 24 hours....
November 12, 2019
A human trial of NMN has recently concluded, and the results are not impressive at all; however, this is perfectly fine because that was not the purpose of the study, and, despite the lackluster results, the study was a success! This might sound strange, but perhaps the words of the study authors may make it...
August 21, 2019
Today, we want to spotlight a recent study showing that boosting nicotinamide adenine dinucleotide (NAD+) levels in mice prevents age-related hearing loss. What is β-Lapachone? β-Lapachone is a quinone-containing compound that was originally isolated from the lapacho tree in South America. It is worth noting that this tree has been used as a herbal medicine...
July 22, 2019
Today, we want to highlight a recent human trial of the popular supplement nicotinamide riboside, a compound that has been shown in mice to restore NAD+ levels. The compound has had impressive results against some aspects of aging in mouse studies, and there is now some more data for NR in humans [1]. What is...
June 24, 2019
Researchers from Washington University School of Medicine in St. Louis have discovered a way to delay aging in mice with a protein that is abundant in the blood of young mice but declines with age. eNAMPT and the NAD salvage pathway That protein is extracellular nicotinamide phosphoribosyltransferase (eNAMPT), and it plays a key role in...