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Tag: Lung Disease

Lung cancer
Scientists have identified the proteins FOXF1 and its downstream target FZD4 as potential targets for treating lung cancer. Upregulating them helps to normalize vasculature in the tumor area and suppresses this lethal type of cancer [1]. Lung cancer and vasculature Lung cancer remains one of the deadliest diseases in the world, accounting for 22% of...
Cell targeting
Researchers publishing in the Journal of Clinical Investigation have developed a new method of screening for compounds, and they found one that appears to directly attack senescent cells involved in lung fibrosis. A disease of senescence What Are Senolytics? Senotherapeutics for Senescent CellsSenolytics work by targeting one of several pro-survival pathways that senescent cells use...
Smoking mouse
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...
Silica dust
A new paper published in Nutrients shows that the well-known NAD+ precursor NMN alleviates lung injury caused by silicate inhalation in wild-type mice. An antioxidant approach to a common problem Nicotinamide mononucleotide (NMN): Benefits and Side EffectsNicotinamide mononucleotide (NMN) is a precursor of the coenzyme NAD+, which serves critical functions in our cells. The decline...
Polluted lungs
A new study published in Nature Medicine suggests that lifelong exposure to tiny airborne particles leads to their accumulation in lymph nodes in the lungs and to impaired immune function [1]. Age-related lung diseases and pollution With age, people become more susceptible to many diseases, with the lungs being one of the most affected organs....
Air Pollution
In a new study published in Ecotoxicology and Environmental Safety, the researchers have shown that air pollution leads to lung function decline accompanied by lung and intestinal microbiome disbalances [1]. Air quality and longevity It is widely accepted that both intrinsic and extrinsic factors influence lifespan. Extrinsic factors include both lifestyle choices and environmental factors...