November 25, 2024
In Aging, researchers have reported that deriving extracellular vesicles from mesenchymal stromal cells (MSCs) in fat tissue has beneficial effects in models of osteoarthritis. Which source to use? Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are...
July 18, 2024
In Aging Cell, researchers have published their findings into why the inflammatory factor IL-6 inhibits cancerous tumors when generated inside the cell. IL-6 affects both senescence and cancer proliferation Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they...
April 15, 2024
A team of researchers has waded into a controversial and contradictory area of study, publishing information on the link between obesity and an inflammatory molecule that increases with aging. A context-dependent molecule What is Inflammaging? Chronic Inflammation and AgingOne of the aging processes consists of a chronic, smoldering background of inflammation that researchers call “inflammaging”.Read...
October 26, 2023
Researchers publishing in Aging have explained a relationship between inflammation, metabolic syndrome, and prostate enlargement. Not so benign Benign prostatic hyperplasia (BPH) is only called 'benign' to differentiate it from another well-known cause of prostate enlargement: prostate cancer. BPH is known to lead to bladder obstruction and lower urinary tract issues. It also coincides with...
October 23, 2023
A new preprint suggests that continuous sleep disruption might drive health problems via increased cellular senescence in visceral fat tissue [1]. Sleep and health Until recently, the impact of sleep on human health was largely overlooked, including for healthcare professionals who work long hours. Now, scientists are beginning to understand that impaired sleep quality drives...
August 07, 2023
Scientists publishing in Nature have explained a key pathway that leads to immune dysfunction and neurodegeneration in aging. Feeling the STING Throughout this paper, the researchers cite other papers demonstrating a cause-and-effect relationship between initial damage and long-term effects. Perturbed mitochondria release their mitochondrial DNA (mtDNA) into the internal liquid (cytosol) of microglia, the helper...