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Tag: Epigenetics

Naked mole rat
A research paper published in Nature by Dr. Vadim Gladyshev and his team has investigated the epigenetic aging of the naked mole rat, an animal whose mortality rate does not appear to increase with age. Why we Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and...
EARD2021 Jacob Kimmel
At Ending Age-Related Diseases 2021, Jacob Kimmel of Calico Labs talked about epigenetic reprogramming, the Yamanaka factors, the dangers involved in restoring living cells to a pluripotent state, and a way forward with reprogramming that might not even involve the Yamanaka factors at all. Script I want to share a pretty short story with you...
Olives
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. KidneyThe kidney's main function is to filter waste products out of the blood and deliver the resulting urine to the bladder. The functional unit of the kidney is called the nephron, and each kidney...
Gene transcription
Transcriptomic results have been published regarding the Shamir Medical Center longitudinal study on hyperbaric oxygen therapy (HBOT), which was conducted between 2016 and 2020 on 35 healthy adults aged 64 and older [1]. Background Recently, we discussed misconceptions from the media on research developing on HBOT for age reversal. The Sheekey Science Show discussed both...
Press the reset button
Today, we chronicle the progress of partial cellular reprogramming and discuss how this powerful treatment may be able to reprogram cells back into a youthful state, at least partially reversing epigenetic alterations, one of the proposed reasons we age. We have created an introduction video about cellular reprogramming and if you would like to learn...
Journal Club
The Journal Club hosted by Dr. Oliver Medvedik returns for another episode on May 25th at noon Eastern / 5 UK time live on our Facebook page. This month, we have one of the authors, Dr. Vadim Gladyshev, joining us, and he will be talking us through this new research. Vadim and his team report...