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Tag: epigenetics

July 14, 2020
In this premier episode of Lifespan News, Brent Nally discusses Unity Biotechnology's human trials of novel senolytic drugs, including a Phase 2 human trial of a senolytic drug for knee osteoarthritis; two proteins that allow LDL cholesterol to enter our cells; Ponce de Leon Health and epigenetic age reversal; the reason why naked mole rats...
June 30, 2020
Today, we want to highlight a press release from Ponce de Leon Health that talks about the results of a pilot consumer trial that the company has recently concluded. The company claims that it has been successful in reducing the epigenetic age of participants by an average of 8.5 years with its dietary supplement Rejuvant....
June 02, 2020
Researchers have proposed a new epigenetic clock designed to measure subtle epigenetic changes in vitro [1]. They hope that their discovery will help to expedite the creation of new anti-aging drugs. Measuring biological age Aging research is all about the difference between chronological and biological age. The former is simply the passage of time, but...
May 20, 2020
Dr. Oliver Medvedik returns to the Journal Club on May 21st, 1:00 PM EDT, live on our Facebook Page and is going to be taking a look at a new study in which researchers claim that they have halved the epigenetic age of old rats using blood factors present in young rats. The paper was...
May 04, 2020
A paper published in Aging has shown that it is possible to treat spinal disc degeneration through altering the epigenetics of macrophages. Macrophages and inflammaging Macrophages are the clean-up crew of the immune system, engulfing and destroying harmful germs, but their polarization is a double-edged sword. On one hand, M1 macrophages serve on the front...
March 24, 2020
Researchers at Stanford University have demonstrated they can rejuvenate human cells, making them more like young cells again, by rewinding an epigenetic aging clock. Epigenetic alterations and aging One of the hallmarks of aging is epigenetic alterations, which are the alterations to gene expression that our cells experience with age. They harm the fundamental functions...