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Tag: epigenetics

January 22, 2020
Recently, Dr. David Sinclair did an AMA ("Ask Me Anything") on Reddit. Events like these, which allow people to ask researchers questions about their work on an open forum, can often turn up interesting responses that are not always uncovered during interviews. We have picked these few questions and answers, but we suggest that you...
November 29, 2019
A team of researchers, including Drs. Vadim Gladyshev and Steve Horvath, recently published a review of DNA methylation aging clocks, which use biomarkers to determine the biological age of a person. Aging causes epigenetic alterations to occur, including changes to DNA methylation, histone modification, transcriptional alterations (variance in gene expression), and remodeling of chromatin (a...
November 08, 2019
A recent open-access study published in Cell Stem Cell has shown that excluding Oct4 from the OSKM cocktail reduces epigenetic aberrations and off-target gene activation. Induced pluripotency and Yamanaka factors Pluripotent stem cells are cells that can become other cell types in the body; during natural development, they create differentiated stem cells and ultimately somatic...
October 25, 2019
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Vadim Gladyshev of Harvard Medical School discussed methods of discovering longevity interventions, including analyzing the genomes of long-lived mammals and...
October 14, 2019
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Dr. Qingsong Zhu, the COO of Insilico Medicine, discussed the use of deep learning in creating biomarkers for aging. Initially...
October 04, 2019
At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge. BioAge is developing a drug discovery platform that uses machine learning and artificial intelligence to discover targets that have the potential to promote healthy lifespan (healthspan) by slowing...