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Tag: DNA Methylation

Epigenetic wrapping
April 12, 2021
A new technique allows researchers to turn epigenetic methylation off and back on again, thus allowing the silencing and unsilencing of certain genes. A CRISPR breakthrough CRISPR/Cas9 is a well-known technology for editing the genome, but its potential for epigenetic editing had never been previously explored. With a directed CRISPR memory writer able to methylate...
binary clock image
March 09, 2021
Scientists have devised a transcriptome-based aging clock that allows for precise measurement of biological age in C. elegans worms and shows promising results in humans as well [1]. The purpose of aging clocks One of the central questions of longevity research is how to measure biological age. If a pathology, genetic difference, lifestyle choice, or...
LifeXtenShow on the tones of DNA
February 04, 2021
In this episode of X10, Nicola explains methylation in the context of language tones, showing how DNA methylation leads to DNA interpretations being slightly different between cells. He also introduces the idea of epigenetic clocks and discusses how gene expression, epigenetic alterations, and methylation are related. HELP SPREAD THE WORD Please connect with us on...
Nucleosome
August 10, 2020
Epigenetic alterations, which are one of the proposed reasons we age, are the changes to gene expression that our cells experience as we get older. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases. Depending on your view, epigenetic alterations are either the result...
DNA clock
July 24, 2020
A team of researchers have developed a tissue-specific clock that can measure the biological age of skin. There is plenty of new evidence that different organs and tissues in our body age at different rates. In particular, the epigenetic state, the pattern of gene expression, of the cells that comprise these different organs and tissues...
Mouse eye
January 23, 2020
A new study has demonstrated that increasing the expression of a single gene was enough to reverse age-related visual decline in the eyes of old mice. Introducing ELOVL2 Elongation of Very Long Chain Fatty Acids Protein 2 (ELOVL2) is both a bit of a tongue twister and a known aging biomarker. The results of a...