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Tag: DNA methylation

August 10, 2020
Epigenetic alterations, which are one of the proposed reasons we age, are the changes to gene expression that our cells experience as we get older. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases. Depending on your view, epigenetic alterations are either the result...
July 24, 2020
A team of researchers have developed a tissue-specific clock that can measure the biological age of skin. There is plenty of new evidence that different organs and tissues in our body age at different rates. In particular, the epigenetic state, the pattern of gene expression, of the cells that comprise these different organs and tissues...
January 23, 2020
A new study has demonstrated that increasing the expression of a single gene was enough to reverse age-related visual decline in the eyes of old mice. Introducing ELOVL2 Elongation of Very Long Chain Fatty Acids Protein 2 (ELOVL2) is both a bit of a tongue twister and a known aging biomarker. The results of a...
October 11, 2019
A team of researchers, including Dr. David Sinclair, has recently made a new study available as a preprint prior to peer review and publication in the journal Cell. DNA damage and the double-strand break Two of the primary hallmarks of aging are genomic instability, which consists of damage to our DNA, and epigenetic alterations, which...
February 15, 2019
Researchers at the Harvard T.H. Chan School of Public Health have discovered a new aging clock that can accurately determine both chronological and biological age in a wide variety of species. Aging and the nucleolus There are two kinds of age: chronological age, which is strictly the number of years that something has lived, and...