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Tag: Cellular Reprogramming

Dividing cells
May 10, 2021
A team of researchers, including Michael West of AgeX Therapeutics, has authored a review paper that posits a fundamental difference between "immortal" germline cells and "mortal" somatic cells. The two types of cells This review paper, which cites 175 other papers, goes back throughout history, discussing the very earliest scientific theories of aging. It talks...
Astrocyte
April 13, 2021
Scientists have successfully reprogrammed astrocytes (a type of brain cell) into healthy neurons in the brains of living mice. This technique could potentially be used for replenishing the neuronal population in people suffering from brain damage and age-related cognitive decline [1]. BrainThe brain is perhaps the most important organ in the body. While many organs...
Mouse eye
December 04, 2020
Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can be reset to become younger again using this approach and are better at repairing damaged tissue. The approach has huge potential in the treatment of...
April 23, 2019
Mesenchymal stem cells (MSCs) have been a topic of great interest in the last decade or so due to their ability to improve tissue regeneration merely by their presence and the secreted signals they give out. Adult MSCs have traditionally been used for regenerative medicine with hit-and-miss results, depending on the quality and age of...
March 20, 2019
We have talked about the potential of partial cellular reprogramming in previous articles, and today, we want to draw attention to a new paper that promises to further refine reversal of epigenetic aging in cells. As we age, our cells experience alterations to their epigenetic markers, and this changes gene expression, which is proposed to...