April 06, 2020
New research shows that resveratrol, a chemical found in red wine, contributes to genomic stability by reducing the occurrence of DNA double-strand breaks and prolongs lifespan in genetically modified mice that are prone to carcinogenic mutations [1]. DSBs and genomic instability Genomic instability, one of the hallmarks of aging, is a condition characterized by frequent...
March 23, 2020
The researchers of a new review have examined the relationship between cellular senescence and bone marrow cancers, looking at how senescence can ultimately fuel cancer development and how malignant cells induce senescence [1]. Senescent cells and cancer As we get older, an increasing number of our cells enter into a state known as senescence, a...
February 11, 2020
At the recent Longevity Therapeutics Conference in San Francisco, we had the chance to interview Lewis Gruber of SIWA Therapeutics and discuss his company's senotherapeutic approach to cancer and senescent cells. He was accompanied by his wife, Misty, who is the CFO of SIWA. Many of our readers are familiar with CAR-T immunotherapy, which has...
January 15, 2020
According to a new study from Harvard researchers, switching to a healthier lifestyle by the time you reach middle age could potentially give you eight to ten more years of healthy life free from age-related diseases. Healthy habits mean a longer, healthier life This new epidemiological study shows that adopting the five habits of eating...
November 13, 2019
Recently, the first attempt in the United States to use the gene editing tool CRISPR to combat cancer appears to have gone well, according to the initial results of a small human trial to determine safety for the approach. Gene editing is a way to permanently change DNA in order to potentially cure a disease...
October 24, 2019
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Jared Fischer of OHSU talked about senescent cancer cells and the intricate relationship between cancer and senescence. He talked about...
