October 19, 2020
Researchers have successfully used the CRISPR/Cas9 gene editing tool to destroy Ewing's sarcoma and chronic myeloid leukemia tumor cells by targeting the fusion genes responsible for these tumors [1]. Fusion genes, a feature in many different types of cancer, arise when a mutation fuses two genes together, which typically happens when the DNA sequence between...
October 13, 2020
In a review paper, a group of scientists highlight a new strategy that addresses the shortcomings of stem cell therapy by adding T cell progenitors to the graft [1]. Adaptive Immune SystemThe adaptive immune system is a marvel that only vertebrates are blessed with. This complex mechanism protects us from a wide variety of threats,...
September 29, 2020
A group of researchers have devised an effective anti-cancer therapy by loading cytokine-coding RNA fragments into lipid nanoparticles and injecting them directly into the tumor [1]. Anti-cancer immunotherapy is a powerful novel strategy that has given hope to millions of cancer patients. The immune system has a few aces up its sleeve when fighting cancer,...
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in many age-related conditions. What are senescent cells? As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do...
June 10, 2020
A possible new role for niacin has been discovered in the fight against brain cancer. An old vitamin Niacin is a form of vitamin B3 and has been a popular supplement since its discovery in 1937 by the researcher Conrad Elvehjem. Niacin is actually nicotinic acid, and it is possible to create it through the...
April 06, 2020
New research shows that resveratrol, a chemical found in red wine, contributes to genomic stability by reducing the occurrence of DNA double-strand breaks and prolongs lifespan in genetically modified mice that are prone to carcinogenic mutations [1]. DSBs and genomic instability Genomic instability, one of the hallmarks of aging, is a condition characterized by frequent...
