Tag: Alzheimer's

A novel therapy based on induced neuronal stem cells shows promise in a mouse model of Alzheimer’s disease – and it can be administered intranasally [1]. Who needs cells? Stem cell therapies have made great strides in recent decades. They have been successfully employed against numerous diseases, from cancer to osteoarthritis. However, storing, transporting, and...

Boosting a key autophagy-related protein discourages a core component of Alzheimer's from taking hold, according to a study published in Aging Cell. Taking out the trash Autophagy is the maintenance process of the cell, in which autophagosomes engulf unwanted organelles and other material and fuse together with lysosomes to be digested. As these unwanted components...

Scientists have shown that long-term intermittent reprogramming limited to hippocampal neurons increases their fitness and improves cognitive function in a mouse model of Alzheimer’s disease [1]. Targeted in time and space Partial cellular reprogramming is one of the hottest directions in longevity research for a reason: it allows to rejuvenate cells without driving them all...

With Alzheimer’s disease, most of the focus has been on neurons. A new study's researchers suggest boosting the process of cellular junk removal in astrocytes, brain cells that perform maintenance tasks, as a new pathway [1]. Looking at a different cell type Accumulation of amyloid beta, a misfolded protein, is undoubtedly one of the hallmarks...

Scientists have found a correlation between the intensity of nighttime outdoor lighting, which can disrupt sleep, and Alzheimer’s disease [1]. Light pollution – heavy consequences Outdoor lights help us with a lot of things, such as illuminating our streets and highways, discouraging crime, and so on. City nightlines and views of Earth at night from...

The results of 10 independently conducted clinical trials suggest that ketogenic diets have a positive impact on the cognitive function of Alzheimer's disease patients [1]. Keto instead of a pill? Despite extensive research, there is stilll no effective treatment for Alzheimer's disease. Therefore, approaches that aim to delay disease through lifestyle changes, such as diet,...