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Tag: Alzheimer's

Journal Club
Journal Club returns on July 27th at noon Eastern / 17:00 UK live on our Facebook page. A new way to look at Alzheimer's The topic for this month will be a new study that challenges the amyloid hypothesis of Alzheimer's disease with new human data. The data suggests that the cognitive impairment that accompanies...
Solving brain puzzle
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid accumulation may be the consequence, not the cause Over 100 years ago, Alois Alzheimer originally identified amyloid-beta plaques in the brains of people with the...
Elderly woman sleeping
Quality sleep is one of the foundations of health, and a new study suggests that poor sleep quality is a major risk factor for developing Alzheimer’s disease and other dementias. Dementia is a rising global problem Worldwide, close to fifty million people currently live with Alzheimer's disease or other forms of dementia. According to the...
Neurons
Scientists have successfully improved learning and memory, as well as neuronal morphology, in Alzheimer’s-prone mice with the help of a gene therapy that upregulates a vital protein [1]. Alzheimer’s disease (AD) has been a notoriously hard problem to crack, despite major R&D investment. AD has long been associated with the accumulation of amyloid-beta (Aß) plaques...
Mouse brain maze
According to a new study, Alzheimer’s disease is connected to inflammaging, which causes B-cells to change their phenotype and hamper amyloid-β (Aβ) removal [1]. Following successful experiments in vivo, the scientists propose B cell depletion as a possible therapy. The darker side of B cells    Alzheimer's disease (AD) is deadly, frustratingly resilient to treatment, and...
Alzheimer's disease
Until now, it was unclear as to whether drugs that clear amyloid, which accumulate in the brain during aging and accompany diseases such as Alzheimer's, have any influence over cognitive decline. Previous studies have aimed to find this out, but results have been inconclusive due to study designs, hard-to-interpret data, and other issues that muddy...