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Tag: Alzheimer's

February 13, 2020
On this informative episode of X10, Giuliano explains proteins and how they misfold, causing the hallmark of aging known as loss of proteostasis- which leads to Alzheimer's disease and other dangerous diseases.  NewsSedeer el-Showk Joins the Lifespan.io TeamFebruary 18, 2020Our plan this year is to significantly expand and develop our news outlet so that...
September 13, 2019
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Today, we're releasing a talk from Dr. Doug Ethell, who announced his company's efforts to combat Alzheimer's disease, describing where...
August 30, 2019
The macrophages resident in the brain and spinal cord appear to be a key element in the progression of Alzheimer's disease, according to the results of a new mouse study. Microglial mayhem As we age, our immune cells become increasingly dysfunctional; once-helpful cells can behave in harmful ways, promoting persistent inflammation, impairing tissue regeneration, and...
August 29, 2019
In a recent study, a team of researchers has discovered that a naturally occurring protein called Lipocalin-type prostaglandin D synthase (L-PGDS) prevents, and can destroy, the protein aggregates associated with Alzheimer's disease. Surprisingly common and with critical functions L-PGDS is a common protein, second only to albumin, in the human brain. It provides several critical...
August 27, 2019
In a recent study, a team from the Neurobiota Research Center in Korea has discovered that reducing gut dysbiosis partially alleviates the cognitive impairment associated with Alzheimer's disease. This may seem puzzling, as the gut and the brain are separate and relatively distant organs, but this research makes sense in the context of chronic inflammation....
July 19, 2019
In a recent study, a group of researchers from Hebrew University-Hadassah Medical School, Feinberg School of Medicine, and Tel Aviv University examined astrocytes in mice and found that these cells exhibited a senescent phenotype that led to neurodegeneration and neurotoxicity [1]. Age-dependent increase in senescent astrocytes adjacent to Aβ plaques Cellular senescence, discovered in 1961...