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Tag: Alzheimer's

Swimming mouse
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer's and outlined the genes involved. What is Niacin? Benefits and Side EffectsNiacin is a form of vitamin B3. It was discovered in 1937 by Conrad Elvehjem and originally used to treat pellagra, a...
Elderly Japanese couple
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory bacterium The researchers begin their paper by noting that mild cognitive impairment (MCI) is associated with memory loss and is frequent precursor of Alzheimer's disease...
Brain genes
A paper published in Cell Metabolism has reported on a metabolic shift in neurons derived from patients with Alzheimer's disease, showing that they express a cancer-like phenotype [1]. Induced neurons Rather than attempting to harvest live neurons from Alzheimer's patients, the researchers chose to create induced neurons (iNs) from the fibroblasts of these patients, comparing...
Severe brain disease
In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on genetics and environment One out of twenty Americans over 85 have Parkinson's disease [1], and seven out of twenty have Alzheimer's [2]. While genes are...
GR15
Gitcoin has launched its 15th funding round and is again supporting projects focused on aging and rejuvenation. An alternative way to fund science Gitcoin is a platform focused on supporting the development of open-source Web3 software. This is a decentralized system based on blockchain technology with the goal of funding "public good" projects that are...
Brain inflammation
Scientists have synthesized a molecule that alleviates Alzheimer's in a mouse model by targeting inflammation [1]. Aβ or inflammation? Two of the most prominent - and probably interconnected - symptoms of Alzheimer's disease are the accumulation of amyloid beta (Aβ) and chronic neuroinflammation. While the first one has been garnering most of the attention, innumerable...

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