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Category: Supplements

Easter Island
We take a look at rapamycin and why some researchers think it could be useful in combating aging. What is rapamycin? Rapamycin is a macrolide, a class of antibiotic that includes erythromycin, roxithromycin, azithromycin, and clarithromycin. Rapamycin exhibits potent antitumor and immunosuppressive activity. Where is rapamycin found? Rapamycin was first discovered in 1972 in the...
NR molecule
Nicotinamide riboside (NR) is part of the B3 vitamin family. Like other forms of vitamin B3, nicotinamide riboside gets converted into nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for life. For this reason, it is often called a NAD+ precursor because it is part of the series of chemical steps that are required to create...
Grapes
Probably best known for its presence in grapes and wine, this popular dietary supplement may have a few tricks up its sleeve. What is resveratrol? Resveratrol is a stilbenoid, a type of natural phenol. It is a phytoalexin, a growth-inhibiting substance created by plant tissues in response to injury or contact with pathogens such as...
Capers are high in quercetin which may help slow down aging.
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. We take a look at this natural compound and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of water-soluble plant compounds. Flavonoids are not created by the body...
Found in grapefruit, spermidine is one of the more interesting polyamines. Some research suggests that spermidine may slow down aging and promote healthy longevity. What is spermidine? Spermidine is a polyamine, meaning it has two or more primary amino groups. It is naturally occurring and is widely encountered in ribosomes and living tissues. It plays a...
Barberries
We take a look at berberine, a popular supplement in the life extension community that is often touted as being similar to metformin. What is berberine? Berberine is an ammonium salt from the protoberberine group of benzylisoquinoline alkaloids. It is part of a group of naturally occurring alkaloids that mostly contain basic nitrogen atoms. Berberine...