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Category: Supplements

Cocoa
A large-scale, randomized, controlled trial has found that in aging adults, cocoa extract does not affect the prevalence of adverse cardiovascular events but decreases their lethality [1]. Rich in flavanols The nutrients that we consume obviously impact our healthspan and lifespan, but studying their effects in a controlled environment in humans is not easy. Most...
Old woman in sunlight
Using a Berlin cohort, a study published in GeroScience has uncovered a link between Vitamin D supplementation and a reduction of epigenetic age. On the back of previous work This study's cohort consisted of 60- to 85-year-old participants in the Berlin Aging Study II (BASE-II). The researchers had previously used data from this cohort to...
Exercising Elderly
A new study published in Cell Reports Medicine shows that urolithin A supplementation improves muscle strength, fitness, and mitochondrial health in overweight, middle-aged adults [1]. Mitophagy in aging and in disease Mitochondrial dysfunction is one of the hallmarks of aging. It is associated with age-related skeletal muscle deterioration, which leads to such functional impairments as...
NMN pills
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. It is a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that may be useful in slowing down...
Sunlight
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and February 2017. After screening procedures and inclusion criteria, 2423...
Skeletal Muscle
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A's effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial  This study is a follow-up to prior work done by the Amazentis company,...