Tag: RNA

The current pandemic has brought mRNA vaccines into the spotlight and have likely sped up the widespread adoption and usage of this technology. Now, a company has its sights set on treating cancer with mRNA technology, and the initial animal data is positive. mRNA steps up to treat cancer mRNA vaccines look like they are...

New research has identified a set of long noncoding RNAs involved in inflammaging and the senescence-associated secretory phenotype (SASP) [1]. These RNAs are conserved across a range of species, including humans, and may prove a valuable avenue for controlling senescence. Age-related RNAs RNA can broadly be divided into protein-coding RNAs and noncoding RNAs, which have...

A massive RNA sequencing effort has identified changes in microRNA associated with Parkinson's. Some of the changes correlated with disease progression, holding out hope that they could be useful as prognostic or diagnostic biomarkers to help guide research and evaluate potential therapies. Pinning down Parkinson's Although Parkinson's disease is the second most common neurodegenerative disease...

In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger of cancer is from its proliferation: its uncontrolled division within the body. This proliferation is explained by the mutated cells exhibiting stem-like properties; in other...

A group of researchers have devised an effective anti-cancer therapy by loading cytokine-coding RNA fragments into lipid nanoparticles and injecting them directly into the tumor [1]. Anti-cancer immunotherapy is a powerful novel strategy that has given hope to millions of cancer patients. The immune system has a few aces up its sleeve when fighting cancer,...

Researchers have developed what can be described as the first precision gene editing tool for mitochondrial DNA (mtDNA). This new tool is different from the well-known CRISPR/Cas9 method of gene editing and should make the study of mitochondrial biology and mitochondrial diseases easier. This new discovery is a game changer Prior to this, creating mouse...