Tag: RNA

A massive RNA sequencing effort has identified changes in microRNA associated with Parkinson's. Some of the changes correlated with disease progression, holding out hope that they could be useful as prognostic or diagnostic biomarkers to help guide research and evaluate potential therapies. Pinning down Parkinson's Although Parkinson's disease is the second most common neurodegenerative disease...

In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger of cancer is from its proliferation: its uncontrolled division within the body. This proliferation is explained by the mutated cells exhibiting stem-like properties; in other...

A group of researchers have devised an effective anti-cancer therapy by loading cytokine-coding RNA fragments into lipid nanoparticles and injecting them directly into the tumor [1]. Anti-cancer immunotherapy is a powerful novel strategy that has given hope to millions of cancer patients. The immune system has a few aces up its sleeve when fighting cancer,...

Researchers have developed what can be described as the first precision gene editing tool for mitochondrial DNA (mtDNA). This new tool is different from the well-known CRISPR/Cas9 method of gene editing and should make the study of mitochondrial biology and mitochondrial diseases easier. This new discovery is a game changer Prior to this, creating mouse...

Researchers from Johns Hopkins University have published a new study that sheds light on skin rejuvenation, and it shares a link with what some cosmetic companies are doing using laser therapy. A link between cosmetics and regeneration During their study, the researchers found that the laser treatments used by cosmetic companies and retinoic acid, which...

Last month, researchers at Johan Auwerx’s lab at the Ecole Polytechnique Fédérale de Lausanne (EPFL) had looked at the connections between RNA-binding proteins and aging. RNA binding proteins (RBPs) play an important part in post-transcriptional control by binding to mRNA. After binding, RBPs can aid in the processing of pre-mRNA as well as mRNA stability,...