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Tag: Reactive Oxygen Species

Killifish
A recent study published in Biogerontology has discovered a potential new aging biomarker and longevity therapeutic target [1]. Isthmin 1 (Ism1) in aging fish  Ism1 is not a well-known protein, but it has been shown to play a role in multiple aspects of biology. It contributes to tumor suppression [2,3], is essential during organ development...
Bifidobacterium
A new publication in Nature Aging has investigated the role of the gut bacteria Bifidobacterium adolescentis in aging and longevity. The Gut MicrobiomeThe gut microbiome is a complex and ever-changing ecosystem populated by a myriad of archaea, eukarya, viruses, and bacteria. Four microbial phyla, Firmicutes, Bacteroides, Proteobacteria, and Actinobacteria, make up 98% of the total...
Oxygen tank
Recent experiments published in the latest issue of Aging associate hyperbaric oxygen therapy with improvements in several biomarkers of skin aging. SkinSkin, as the most readily visible organ of the human body, is one of the first to let us know that we are getting older. Our skin goes beyond appearance; it protects our internal...
Heart Inflammation
A team of Chinese researchers has outlined the cellular link between age-related inflammation (inflammaging) and the physical aging of heart muscle cells (cardiomyocytes). NLRP3 and why it matters We have previously discussed the NLRP3 inflammasome, which releases inflammatory cytokines upon exposure to irritants [1], including reactive oxygen species (ROS) [2]. The researchers hypothesized that ROS,...
Unexpected treasure
Researchers have found that zoledronate, a drug used to treat osteoporosis, has unexpected life-extending properties in human beings, and they confirmed these findings in a fruit fly study. The original unexpected findings Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk of osteoporosis-related bone fractures. It is well-absorbed into the...
Glucosamine is a polysaccharide that naturally occurs in cartilaginous joint tissues and is involved in protein and lipid synthesis. Glucosamine is also present in other tissues, such as skin, nails, bones, and ligaments. Synovial fluid contains glucosamine and occupies the space between joints, helping to reduce the friction of joint surfaces. Glucosamine is commonly taken...