September 28, 2022
In a new study published in Scientific Reports, researchers have uncovered the molecular mechanism underlying the link between obesity and joint degeneration [1]. Obesity and osteoarthritis Obesity accelerates aging and is associated with several age-associated diseases, including osteoarthritis, an inflammatory condition that leads to joint degeneration. Obesity is often accompanied by low-grade chronic inflammation, which...
August 30, 2022
Scientists have shown that intravenous delivery of mesenchymal stem cells, which has some advantages over the more conventional intra-articular injection, alleviates age-related osteoarthritis and decreases inflammation in guinea pigs [1]. Systemic administration Osteoarthritis, a degenerative joint disease, is one of the most common causes of disability in old age. By limiting the ability to maintain...
July 18, 2022
Publishing in Aging, a team of Spanish researchers has found that changing the mitochondria of standard Black 6 mice leads to marked improvements in joint health. Conplastic mice The Black 6 mouse is well-known in research as a standard in the industry. However, it is not nearly a perfect mouse in terms of ability or...
February 15, 2022
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others that shorten our healthspan rather than lifespan, making the...
January 06, 2022
A study published in Aging has found that osteopontin's effects on bone remodeling may be at least partially responsible for osteoarthritis. BoneBone tissue serves as the primary structural component of our bodies. It protects our delicate inner organs, plays a key role in whole body calcium, phosphorus, and acid-base homeostasis, and allows movement to occur...
December 21, 2021
A new study shows that even low levels of physical activity are very good for your muscles, bones, and joints, but exercising too much can potentially harm you [1]. The unholy trinity Sarcopenia, osteoporosis, and osteoarthritis are the trio of age-related diseases that affect, respectively, muscles, bones, and joints. Sarcopenia is the progressive loss of...
