Tag: NAD+

A new mouse study published in Cell Reports has shown that a metabolic precursor of the coenzyme NAD+ rejuvenates oocytes (egg cells), restoring fertility [1]. The oldest cells In humans, female fertility begins to decline near the end of the third decade of life, long before other markers of aging appear. This age-related decline is...

Mitochondria provide our cells with the energy they need to function, and they become increasingly dysfunctional as we age. A new study suggests that mitochondrial rejuvenation in the context of restoring healthy blood flow and neurovascular health might be possible with the popular supplement NMN. Rejuvenation of aged mitochondria The mitochondria are the power stations...

Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn't a particularly good birthday present. (Wow, what'd I get this year? Just what I didn't want: sarcopenia and hearing loss!) Given...

Recently, Dr. David Sinclair did an AMA ("Ask Me Anything") on Reddit. Events like these, which allow people to ask researchers questions about their work on an open forum, can often turn up interesting responses that are not always uncovered during interviews. We have picked these few questions and answers, but we suggest that you...

A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes that occur in the microbiome [1]. The microbiome The gut microbiome is a complex ecosystem of bacteria, archaea, eukarya, and viruses that live inside of...

A human trial of NMN has recently concluded, and the results are not impressive at all; however, this is perfectly fine because that was not the purpose of the study, and, despite the lackluster results, the study was a success! This might sound strange, but perhaps the words of the study authors may make it...