November 22, 2022
A paper published in the journal Biosensors and Bioelectronics has caused a stir in the longevity community by showing that nicotinamide riboside (NR), a precursor to NAD+, makes tumors more aggressive in a mouse model [1]. Using a novel diagnostic tool In this new paper, the researchers employed a well-known technique called bioluminescence imaging [2]...
November 14, 2022
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer's and outlined the genes involved. What is Niacin? Benefits and Side EffectsNiacin is a form of vitamin B3. It was discovered in 1937 by Conrad Elvehjem and originally used to treat pellagra, a...
August 31, 2022
In a preprint published in bioRxiv, scientists have shown that long-term supplementation of nicotinamide riboside (NR), a NAD+ precursor, alleviates the progression of age-related hearing loss in a mouse model [1]. An overlooked hearing impairment Globally, age-related hearing loss (ARHL) is the most common sensory deficit of older people. Moreover, it is associated with several...
July 25, 2022
Scientists have shown that the effectiveness of natural killer cells, a crucial component of the immune system, is directly linked to NAD+ levels [1]. Naturally deadly Natural killer cells (NK) are an important part of the innate immune system. They got this designation, in arguably the best act of naming in the history of cellular...
June 06, 2022
On this episode of Lifespan News, Ryan O'Shea discusses a study showing that NMN increases NAD+ in human beings. Script The results of a recently published human trial suggest that NMN may have an anti-aging effect in humans, but are these results to be believed? We’ll explore the study, and some additional information you’ll want...
June 02, 2022
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. It is a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that may be useful in slowing down...
