Tag: NAD+

According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility. The study also showed that NMN treatment can restore the metabolic balance in aging mouse oocytes, rescuing fertility. Defective eggs Although malfunctioning of mitochondria and the accumulation of mutations in mitochondrial...

This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the previous part, you can find it here. Today, we are continuing our look at some of the evidence for the age-related decline of NAD+ in humans and some of the likely reasons why this happens....

There has been considerable debate around the age-related decline of NAD+, particularly regarding whether or not it occurs in humans as it does in other species, such as mice. Today, as part of a two-part special, we are going to be taking a look at some of the evidence for the age-related decline of NAD+...

A team of researchers have discovered a novel way to study the process of hair graying, finding it potentially reversible and linked to psychological stress. The abundant anecdotal evidence of hair graying overnight (or, as Shakespeare put it in Henry IV: "Thy father's beard is turned white with the news"), may have finally received a...

Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it must divide to create a human being, the oocyte is the largest cell in the human body, and it contains far more mitochondria than any...

Researchers have concluded a human trial using niacin, a very old vitamin discovered over 80 years ago, and have shown that it can increase the presence of an energy compound essential to cellular function. Niacin and NAD+ Niacin is a form of water-soluble vitamin B3 and has been known since American biochemist Conrad Elvehjem identified...