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Tag: LifeXtenShow

April 12, 2021
In this episode of X10, we discuss the concept of intermittent fasting: what it is, how it differs from caloric restriction, whether or not it can make you live longer or healthier, and the methods of going about it. Script This is part of a series of videos on diet and longevity. Last time, we...
Does death give life meaning? No, not really.
March 29, 2021
In this episode of X10, we discuss what gives life meaning and exactly what role that the ending of life plays in that meaning. Check out the Dog Aging Project, which is run by cool people trying to give our pets longer, healthy lives: http://www.dogagingproject.org Script Do any of these quotes sound familiar to you?...
X10 Caloric Restriction Thumbnail
March 15, 2021
In this episode of X10, we discuss the practice of caloric restriction along with its effects, which involve the TOR signaling pathway, epigenetic alterations, and DNA repair.  Sources Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R. (2009) Caloric restriction delays...
X10 Caring about Aging
March 01, 2021
In this episode of X10, we discuss three reasons why people don't care about curing aging. Getting people to care about elderly dying from a deadly disease is relatively easy, but getting them to care about the cause of their frailty and immune susceptibility, aging itself, is a bit different.  Sources The elderly are...
LifeXtenShow on cellular rejuvenation
February 15, 2021
In this episode of X10, Nicola explains a way to epigenetically reset cells using the OSKM Yamanaka factors, putting them back into a pluripotent stem cell state. These factors have also been experimentally shown to restore cells to youth in other ways, and it is also possible to carefully use these factors to make cells...
LifeXtenShow on the tones of DNA
February 04, 2021
In this episode of X10, Nicola explains methylation in the context of language tones, showing how DNA methylation leads to DNA interpretations being slightly different between cells. He also introduces the idea of epigenetic clocks and discusses how gene expression, epigenetic alterations, and methylation are related. HELP SPREAD THE WORD Please connect with us on...