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Tag: João Pedro de Magalhães

Dinosaur chasing mammal
A prominent geroscientist suggests that more than 100 million years of saurian domination might have deprived mammals of longevity-promoting traits that are found in today’s reptiles [1]. The longevity bottleneck Today, mammals rule the world, but, sadly, we only have an average of 80 years to enjoy our superiority. That's a lot by mammalian standards:...
Dividing cell
In a preprint paper published on bioRxiv, researchers including João Pedro de Magalhães have gotten a glimpse at how stemness declines across tissues with aging. Using AI to get a grasp on stemness Why we Age: Stem Cell ExhaustionStem cell exhaustion is the age-related deficiency of stem cells. This particular hallmark is directly responsible for...
Joao Pedro de Magalhaes
Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of YouthBio Therapeutics, a US-based biotech company that develops rejuvenation gene therapies based on partial reprogramming by Yamanaka factors. Last year, he co-authored The hoverfly and...
EARD2021 Joao Pedro de Magalhaes
In his talk at Ending Age-Related Diseases 2021, João Pedro de Magalhães discussed the difference between longevity and rejuvenation along with the need for more ambitious research. Script I think it's a very exciting time to be working on longevity. I prepared a slightly different presentation like I did two years ago when I was...
The Hallmarks of aging are the nine proposed reasons we age.
The hallmarks of aging, as presented in a 2013 paper [1], have been useful but do not provide a genuine explanatory paradigm, argue David Gems of University College London and João Pedro de Magalhães of the University of Liverpool in a pre-print paper [2]. They propose that biogerontology would benefit from replacing the hallmarks with...
Dr. João Pedro de Magalhães is a Professor at the University of Liverpool, England, where he studies aging and longevity at the genetic level, and he is also an affiliate Principal Investigator in the Neuroendocrinology and Aging Group at the University of Coimbra, Portugal. Dr. de Magalhães has built the Human Ageing Genomic Resources (HAGR),...