January 31, 2023
Scientists have shown that a longevity-associated variant of the BPIFB4 gene protects cardiovascular health, including when introduced by viral vectors [1]. All you need is LAV Among age-related pathologies, cardiovascular disease is the most prolific killer, claiming about 700,000 victims every year in the US alone and as many as 18 million worldwide. However, some...
January 30, 2023
Research published in Cell Stem Cell has described how previously unmodified animals have been given regenerative abilities akin to those of zebrafish, restoring their heart muscle after injury. A TREE of life This study is introduced with a discussion of gene therapy as a field, noting clinical approval for gene therapies against multiple genetic diseases...
December 22, 2022
A paper just published in Nature Aging has explained how changes to the lamina contribute to heart weakness in model organisms. A protective enclosure for genetic stability Lamin proteins enclose the nucleus in the lamina, the cellular envelope that contains and protects DNA. In progeria, a mutation of the gene that codes for the Lamin...
October 11, 2022
In ESC Heart Failure, researchers have commented about the correlation between a poor gut microbiome and aging of the heart [1]. The microbiome is important in aging Research increasingly suggests that the quality and composition of the gut microbiome may play a role as important as exercise on health. The gut microbiome is a living...
June 22, 2022
A study published in Alzheimer's Research & Therapy has shown that low-dose aspirin affects Alzheimer's disease and vascular dementia only in the presence of coronary heart disease. A well-known preventative Acetylsalicylic acid, more commonly known as aspirin, is often taken at a steady, low dose of 100 to 300 milligrams a day in order to...
March 31, 2022
Publishing in Aging, researchers from the Chengdu Jinjiang Hospital in China have discovered that caloric restriction is less effective on mice previously fed a high-calorie diet. Well-known effects In their introduction, the researchers discuss what caloric restriction is known to do, citing papers that show its effects on autophagy [1], inflammation [2], nutrient sensing [3],...
