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Tag: Clinical Trials

Longeveron
Longeveron has just announced the first data from its Phase 2b clinical trial that targets frailty with Lomecel-B, an MSC-based cell therapy. A longevity strategy built in More and more, biotech start-ups are applying longevity strategies to their therapeutic pipelines. Among them, Longeveron stands out as one of the few companies taking a cell-based approach....
Strawberries
We take a look at the popular supplement fisetin and see how it stacks up as a potential anti-aging supplement. What is Fisetin? Fisetin is a plant polyphenol and part of the flavonoid group in the flavonol sub-category.  It is present in many trees and plants, including Eudicotyledons, Acacia greggii, Quebracho colorado, Rhus cotinus, and...
The Sheekey Science Show on fisetin
In this video, the Sheekey Science Show explores fisetin, a flavonoid that is found in strawberries and shown to have senolytic effects. This compound, a polyphenol like resveratrol and quercetin, has been shown to somewhat activate SIRT1, which enhances longevity, while eliminating harmful senescent cells in mice, as proven by the reduction of cells that...
Unity biotechnology logo
Unity Biotechnology has recently announced the launch of its Phase 1 study of UBX1325 for patients with diabetic macular edema. The drug is designed to remove problematic senescent cells from the body which accumulate as we get older and are a reason we age. Why we Age: Cellular SenescenceAs your body ages, more of your...
Unity biotechnology logo
While we enjoy reporting positive news, we do occasionally have to report bad news, and today is one of those days. There has been some disappointing news from UNITY Biotechnology with the release of its Phase 2 senolytic trial of its candidate drug UBX0101. SOUTH SAN FRANCISCO, Calif., Aug. 17, 2020 (GLOBE NEWSWIRE) -- UNITY...
Gene editing
Recently, the first attempt in the United States to use the gene editing tool CRISPR to combat cancer appears to have gone well, according to the initial results of a small human trial to determine safety for the approach. Gene editing is a way to permanently change DNA in order to potentially cure a disease...